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Page 1
Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation.
Garcia GL, Orellana T, Gorecki G, Frisbie L, Baruwal R, Suresh S, Goldfeld E, Beddows I, MacFawn IP, Britt AK, Hale MM, Elhaw AT, Isett BR, Hempel N, Bao R, Shen H, Buckanovich RJ, Finkel T, Drapkin R, Soong TR, Bruno TC, Atiya HI, Coffman LG. Garcia GL, et al. Among authors: macfawn ip. Cancer Discov. 2025 Jun 3;15(6):1203-1224. doi: 10.1158/2159-8290.CD-24-0805. Cancer Discov. 2025. PMID: 40084985 Free PMC article.
Dysfunctional CD11c-CD21- extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer.
Ruffin AT, Casey AN, Kunning SR, MacFawn IP, Liu Z, Arora C, Rohatgi A, Kemp F, Lampenfeld C, Somasundaram A, Rappocciolo G, Kirkwood JM, Duvvuri U, Seethala R, Bao R, Huang Y, Cillo AR, Ferris RL, Bruno TC. Ruffin AT, et al. Among authors: macfawn ip. Sci Transl Med. 2025 Feb 19;17(786):eadh1315. doi: 10.1126/scitranslmed.adh1315. Epub 2025 Feb 19. Sci Transl Med. 2025. PMID: 39970232
Dendritic cells type 1 control the formation, maintenance, and function of tertiary lymphoid structures in cancer.
Mattiuz R, Boumelha J, Hamon P, Le Berichel J, Vaidya A, Soong BY, Halasz L, Radkevich E, Kim HM, Park MD, Donne R, Troncoso L, D'Souza D, Kaiza ME, MacFawn IP, Belabed M, Mestrallet G, Humblin E, Merand R, Hennequin C, Ioannou G, Ozbey S, Figueiredo I, Hegde S, Tepper A, Merarda H, Nemeth E, Goldstein S, Reid AM, Noureddine M, Tabachnikova A, Ahmed J, Polydorides AD, Bhardwaj N, Lujambio A, Chen Z, Kozlova EG, Kim-Schulze S, Brody JD, Schotsaert M, Moussion C, Gnjatic S, Sautès-Fridman C, Fridman WH, Roudko V, Brown BD, Marron TU, Cyster JG, Salmon H, Bruno TC, Joshi NS, Kamphorst AO, Merad M. Mattiuz R, et al. Among authors: macfawn ip. bioRxiv [Preprint]. 2024 Dec 27:2024.12.27.628014. doi: 10.1101/2024.12.27.628014. bioRxiv. 2024. PMID: 39763802 Free PMC article. Preprint.
Stromal mediated DNA damage promotes high grade serous ovarian cancer initiation.
Garcia GL, Orellana T, Gorecki G, Frisbie LG, Baruwal R, Goldfield E, Beddows I, MacFawn IP, Britt AK, Hale MM, Shen H, Buckanovich R, Finkel T, Drapkin R, Soong TR, Bruno TC, Atiya HI, Coffman L. Garcia GL, et al. Among authors: macfawn ip. bioRxiv [Preprint]. 2024 May 28:2024.05.23.595550. doi: 10.1101/2024.05.23.595550. bioRxiv. 2024. PMID: 38853994 Free PMC article. Preprint.
Expression of lymphoid structure-associated cytokine/chemokine gene transcripts in tumor and protein in serum are prognostic of melanoma patient outcomes.
Karapetyan L, AbuShukair HM, Li A, Knight A, Al Bzour AN, MacFawn IP, Thompson ZJ, Chen A, Yang X, Dadey R, Karunamurthy A, De Stefano DV, Sander C, Kunning SR, Najjar YG, Davar D, Luke JJ, Gooding W, Bruno TC, Kirkwood JM, Storkus WJ. Karapetyan L, et al. Among authors: macfawn ip. Front Immunol. 2023 Jun 22;14:1171978. doi: 10.3389/fimmu.2023.1171978. eCollection 2023. Front Immunol. 2023. PMID: 37435077 Free PMC article.