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Long-term editing of brain circuits in mice using an engineered electrical synapse.
Ransey E, Thomas GE, Wisdom E, Almoril-Porras A, Bowman R, Adamson E, Walder-Christensen KK, White JA, Hughes DN, Schwennesen H, Ferguson C, Tye KM, Mague SD, Niu L, Wang ZW, Colón-Ramos D, Hultman R, Bursac N, Dzirasa K. Ransey E, et al. Among authors: colon ramos d. bioRxiv [Preprint]. 2025 Mar 26:2025.03.25.645291. doi: 10.1101/2025.03.25.645291. bioRxiv. 2025. PMID: 40196531 Free PMC article. Preprint.
Specific configurations of electrical synapses filter sensory information to drive choices in behavior.
Almoril-Porras A, Calvo AC, Niu L, Beagan J, Hawk JD, Aljobeh A, Wisdom EM, Ren I, Díaz-García M, Wang ZW, Colón-Ramos DA. Almoril-Porras A, et al. bioRxiv [Preprint]. 2023 Aug 3:2023.08.01.551556. doi: 10.1101/2023.08.01.551556. bioRxiv. 2023. Update in: Cell. 2025 Jan 09;188(1):89-103.e13. doi: 10.1016/j.cell.2024.11.037. PMID: 37577611 Free PMC article. Updated. Preprint.
Concrete steps to diversify the scientific workforce.
Tilghman S, Alberts B, Colón-Ramos D, Dzirasa K, Kimble J, Varmus H. Tilghman S, et al. Science. 2021 Apr 9;372(6538):133-135. doi: 10.1126/science.abf9679. Science. 2021. PMID: 33833113 No abstract available.
Programmed Cell Death Modifies Neural Circuits and Tunes Intrinsic Behavior.
Kochersberger A, Torkashvand MM, Lee D, Baskoylu S, Sengupta T, Koonce N, Emerson CE, Patel NV, Colón-Ramos D, Flavell S, Horvitz HR, Venkatachalam V, Hammarlund M. Kochersberger A, et al. Among authors: colon ramos d. bioRxiv [Preprint]. 2023 Sep 25:2023.09.11.557249. doi: 10.1101/2023.09.11.557249. bioRxiv. 2023. PMID: 37745399 Free PMC article. Preprint.
Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9.
Yang S, Park D, Manning L, Hill SE, Cao M, Xuan Z, Gonzalez I, Dong Y, Clark B, Shao L, Okeke I, Almoril-Porras A, Bai J, De Camilli P, Colón-Ramos DA. Yang S, et al. Neuron. 2022 Mar 2;110(5):824-840.e10. doi: 10.1016/j.neuron.2021.12.031. Epub 2022 Jan 21. Neuron. 2022. PMID: 35065714 Free PMC article.
74 results