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High-throughput screen of 100 000 small molecules in C9ORF72 ALS neurons identifies spliceosome modulators that mobilize G4C2 repeat RNA into nuclear export and repeat associated non-canonical translation.
Luteijn MJ, Bhaskar V, Trojer D, Schürz M, Mahboubi H, Handl C, Pizzato N, Pfeifer M, Dafinca R, Voshol H, Giorgetti E, Manneville C, Garnier IPM, Müller M, Zeng F, Buntin K, Markwalder R, Schröder H, Weiler J, Khar D, Schuhmann T, Groot-Kormelink PJ, Keller CG, Farmer P, MacKay A, Beibel M, Roma G, D'Ario G, Merkl C, Schebesta M, Hild M, Elwood F, Vahsen BF, Ripin N, Clery A, Allain F, Labow M, Gabriel D, Chao JA, Talbot K, Nash M, Hunziker J, Meisner-Kober NC. Luteijn MJ, et al. Among authors: muller m. Nucleic Acids Res. 2025 Apr 10;53(7):gkaf253. doi: 10.1093/nar/gkaf253. Nucleic Acids Res. 2025. PMID: 40207633 Free PMC article.
A highly potent, orally bioavailable pyrazole-derived cannabinoid CB2 receptor-selective full agonist for in vivo studies.
Chicca A, Batora D, Ullmer C, Caruso A, Fingerle J, Hartung T, Degen R, Müller M, Grether U, Pacher P, Gertsch J. Chicca A, et al. Among authors: muller m. bioRxiv [Preprint]. 2024 Apr 29:2024.04.26.591311. doi: 10.1101/2024.04.26.591311. bioRxiv. 2024. Update in: ACS Pharmacol Transl Sci. 2024 Jul 09;7(8):2424-2438. doi: 10.1021/acsptsci.4c00269. PMID: 38903103 Free PMC article. Updated. Preprint.
Early innate immune response and evolution of a SARS-CoV-2 furin cleavage site inactive variant in bat cells.
Baid K, Shrivastava S, Luc J, Richard D, Aguiar JA, Machado Y, Aicher SM, Siwak KC, LeBlanc EV, Khatooni Z, Lokugamage KG, Vu MN, Morgan A, Bhuinya A, Chiok KR, Nguyen HT, Stacey HD, Scruten E, Prysliak T, Yim W, McArthur AG, Miller MS, Wilson HL, Capellini T, Faure PA, Liu Q, Mubareka S, Menachery VD, Mossman K, Müller MA, Drosten C, Colpitts CC, Jouvenet N, Overall CM, Doxey AC, Banerjee A. Baid K, et al. Among authors: muller ma. Cell Rep. 2025 Jul 1;44(7):115929. doi: 10.1016/j.celrep.2025.115929. Online ahead of print. Cell Rep. 2025. PMID: 40608518
Shprintzen-Goldberg syndrome: follow-up of the cardiovascular features in an international cohort of 29 patients with SGS.
Bouhatous YM, Arnaud P, Jondeau G, Bonneau D, Rouleau F, Plessis G, Vincent A, Labombarda F, Maragnes P, Delanne J, Muller M, Coubes C, Bredy C, Gouya L, Odent S, Basquin A, Dupuis-Girod S, Barthelet M, Ginglinger E, Delobel B, Vaksmann G, Alessandri JL, Arsac LA, Thomas E, Julia S, Chesneau B, Dulac Y, Callewaert B, Loeys B, Vaerle M, Menke LA, Groenink M, Ades L, Ballesta-Martinez MJ, Shanske AL, Tinschert S, Gehle P, Thauvin-Robinet C, Eicher JC, Falcon-Eicher S, Boileau C, Binquet C, Hanna N, Faivre L. Bouhatous YM, et al. Among authors: muller m. J Med Genet. 2025 Jun 25:jmg-2024-110341. doi: 10.1136/jmg-2024-110341. Online ahead of print. J Med Genet. 2025. PMID: 40562530 Free article.
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