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PCI-DB: a novel primary tissue immunopeptidome database to guide next-generation peptide-based immunotherapy development.
Lemke S, Dubbelaar ML, Zimmermann P, Bauer J, Nelde A, Hoenisch Gravel N, Scheid J, Wacker M, Jung S, Dengler A, Maringer Y, Rammensee HG, Gouttefangeas C, Fillinger S, Bilich T, Heitmann JS, Nahnsen S, Walz JS. Lemke S, et al. Among authors: dubbelaar ml. J Immunother Cancer. 2025 Apr 15;13(4):e011366. doi: 10.1136/jitc-2024-011366. J Immunother Cancer. 2025. PMID: 40234091 Free PMC article.
Warehouse-based, immunopeptidome-guided design of personalised peptide vaccines shows feasibility in clinical trial evaluation in CLL patients.
Heitmann JS, Jung S, Wacker M, Maringer Y, Nelde A, Bauer J, Denk M, Hoenisch-Gravel N, Richter M, Oezbek MT, Dubbelaar ML, Bilich T, Pumptow M, Martus P, Illerhaus G, Denzlinger C, Steinbach F, Aulitzky WE, Müller MR, Dörfel D, Rammensee HG, Salih HR, Walz JS. Heitmann JS, et al. Among authors: dubbelaar ml. Front Immunol. 2024 Nov 26;15:1482715. doi: 10.3389/fimmu.2024.1482715. eCollection 2024. Front Immunol. 2024. PMID: 39660140 Free PMC article. Clinical Trial.
TOFIMS mass spectrometry-based immunopeptidomics refines tumor antigen identification.
Hoenisch Gravel N, Nelde A, Bauer J, Mühlenbruch L, Schroeder SM, Neidert MC, Scheid J, Lemke S, Dubbelaar ML, Wacker M, Dengler A, Klein R, Mauz PS, Löwenheim H, Hauri-Hohl M, Martin R, Hennenlotter J, Stenzl A, Heitmann JS, Salih HR, Rammensee HG, Walz JS. Hoenisch Gravel N, et al. Among authors: dubbelaar ml. Nat Commun. 2023 Nov 17;14(1):7472. doi: 10.1038/s41467-023-42692-7. Nat Commun. 2023. PMID: 37978195 Free PMC article.
A T-cell antigen atlas for meningioma: novel options for immunotherapy.
Medici G, Freudenmann LK, Velz J, Wang SS, Kapolou K, Paramasivam N, Mühlenbruch L, Kowalewski DJ, Vasella F, Bilich T, Frey BM, Dubbelaar ML, Patterson AB, Zeitlberger AM, Silginer M, Roth P, Weiss T, Wirsching HG, Krayenbühl N, Bozinov O, Regli L, Rammensee HG, Rushing EJ, Sahm F, Walz JS, Weller M, Neidert MC. Medici G, et al. Among authors: dubbelaar ml. Acta Neuropathol. 2023 Aug;146(2):173-190. doi: 10.1007/s00401-023-02605-w. Epub 2023 Jun 27. Acta Neuropathol. 2023. PMID: 37368072 Free PMC article.
The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination.
Mühlenbruch L, Abou-Kors T, Dubbelaar ML, Bichmann L, Kohlbacher O, Bens M, Thomas J, Ezić J, Kraus JM, Kestler HA, von Witzleben A, Mytilineos J, Fürst D, Engelhardt D, Doescher J, Greve J, Schuler PJ, Theodoraki MN, Brunner C, Hoffmann TK, Rammensee HG, Walz JS, Laban S. Mühlenbruch L, et al. Among authors: dubbelaar ml. Br J Cancer. 2023 May;128(9):1777-1787. doi: 10.1038/s41416-023-02197-y. Epub 2023 Feb 23. Br J Cancer. 2023. PMID: 36823366 Free PMC article.
Epigenetic regulation of innate immune memory in microglia.
Zhang X, Kracht L, Lerario AM, Dubbelaar ML, Brouwer N, Wesseling EM, Boddeke EWGM, Eggen BJL, Kooistra SM. Zhang X, et al. Among authors: dubbelaar ml. J Neuroinflammation. 2022 May 14;19(1):111. doi: 10.1186/s12974-022-02463-5. J Neuroinflammation. 2022. PMID: 35568856 Free PMC article.
20 results