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Page 1
EcDNA-borne PVT1 fusion stabilizes oncogenic mRNAs.
Yi H, Zhang S, Swinderman J, Wang Y, Kanakaveti V, Hung KL, Wong IT, Srinivasan S, Curtis EJ, Bhargava-Shah A, Li R, Jones MG, Luebeck J, Zhao Y, Belk JA, Kraft K, Shi Q, Yan X, Pritchard SK, Liang FM, Felsher DW, Gilbert LA, Bafna V, Mischel PS, Chang HY. Yi H, et al. Among authors: curtis ej. bioRxiv [Preprint]. 2025 Apr 3:2025.04.01.646515. doi: 10.1101/2025.04.01.646515. bioRxiv. 2025. PMID: 40236070 Free PMC article. Preprint.
Enhancing transcription-replication conflict targets ecDNA-positive cancers.
Tang J, Weiser NE, Wang G, Chowdhry S, Curtis EJ, Zhao Y, Wong IT, Marinov GK, Li R, Hanoian P, Tse E, Mojica SG, Hansen R, Plum J, Steffy A, Milutinovic S, Meyer ST, Luebeck J, Wang Y, Zhang S, Altemose N, Curtis C, Greenleaf WJ, Bafna V, Benkovic SJ, Pinkerton AB, Kasibhatla S, Hassig CA, Mischel PS, Chang HY. Tang J, et al. Among authors: curtis ej. Nature. 2024 Nov;635(8037):210-218. doi: 10.1038/s41586-024-07802-5. Epub 2024 Nov 6. Nature. 2024. PMID: 39506153 Free PMC article.
Disparate Pathways for Extrachromosomal DNA Biogenesis and Genomic DNA Repair.
Rose JC, Belk JA, Wong IT, Luebeck J, Horn HT, Daniel B, Jones MG, Yost KE, Hung KL, Kolahi KS, Curtis EJ, Kuo CJ, Bafna V, Mischel PS, Chang HY. Rose JC, et al. Among authors: curtis ej. Cancer Discov. 2025 Jan 13;15(1):69-82. doi: 10.1158/2159-8290.CD-23-1117. Cancer Discov. 2025. PMID: 39109936 Free PMC article.
Coordinated inheritance of extrachromosomal DNAs in cancer cells.
Hung KL, Jones MG, Wong IT, Curtis EJ, Lange JT, He BJ, Luebeck J, Schmargon R, Scanu E, Brückner L, Yan X, Li R, Gnanasekar A, Chamorro González R, Belk JA, Liu Z, Melillo B, Bafna V, Dörr JR, Werner B, Huang W, Cravatt BF, Henssen AG, Mischel PS, Chang HY. Hung KL, et al. Among authors: curtis ej. Nature. 2024 Nov;635(8037):201-209. doi: 10.1038/s41586-024-07861-8. Epub 2024 Nov 6. Nature. 2024. PMID: 39506152 Free PMC article.
Oxidative Stress is a shared characteristic of ME/CFS and Long COVID.
Shankar V, Wilhelmy J, Curtis EJ, Michael B, Cervantes L, Mallajosyula VA, Davis RW, Snyder M, Younis S, Robinson WH, Shankar S, Mischel PS, Bonilla H, Davis MM. Shankar V, et al. Among authors: curtis ej. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592477. doi: 10.1101/2024.05.04.592477. bioRxiv. 2024. PMID: 38746454 Free PMC article. Preprint.
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
Bi J, Khan A, Tang J, Armando AM, Wu S, Zhang W, Gimple RC, Reed A, Jing H, Koga T, Wong IT, Gu Y, Miki S, Yang H, Prager B, Curtis EJ, Wainwright DA, Furnari FB, Rich JN, Cloughesy TF, Kornblum HI, Quehenberger O, Rzhetsky A, Cravatt BF, Mischel PS. Bi J, et al. Among authors: curtis ej. Cell Rep. 2021 Nov 2;37(5):109957. doi: 10.1016/j.celrep.2021.109957. Cell Rep. 2021. PMID: 34731610 Free PMC article.
Investigations into the DNA-binding mode of doxorubicinone.
Tartakoff SS, Finan JM, Curtis EJ, Anchukaitis HM, Couture DJ, Glazier S. Tartakoff SS, et al. Among authors: curtis ej. Org Biomol Chem. 2019 Feb 13;17(7):1992-1998. doi: 10.1039/c8ob02344a. Org Biomol Chem. 2019. PMID: 30406253
16 results