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The development of a PET radiotracer for imaging alpha synuclein aggregates in Parkinson's disease.
Tian GL, Hsieh CJ, Guarino DS, Graham TJA, Lengyel-Zhand Z, Schmitz A, Chia WK, Young AJ, Crosby JG, Plakas K, Huang T, Jiang H, Yu Y, Hou C, Lee H, Petersson EJ, Giannakoulias S, O'Shea J, Kotzbauer P, Tu Z, Mathis CA, Mach RH. Tian GL, et al. Among authors: mathis ca. RSC Med Chem. 2025 Apr 3;16(6):2743-53. doi: 10.1039/d5md00057b. Online ahead of print. RSC Med Chem. 2025. PMID: 40256311 Free article.
Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search.
Janssen B, Tian G, Lengyel-Zhand Z, Hsieh CJ, Lougee MG, Riad A, Xu K, Hou C, Weng CC, Lopresti BJ, Kim HJ, Pagar VV, Ferrie JJ, Garcia BA, Mathis CA, Luk K, Petersson EJ, Mach RH. Janssen B, et al. Among authors: mathis ca. Mol Imaging Biol. 2023 Aug;25(4):704-719. doi: 10.1007/s11307-023-01814-9. Epub 2023 Mar 29. Mol Imaging Biol. 2023. PMID: 36991273 Free PMC article.
A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy.
Kim HY, Chia WK, Hsieh CJ, Saturnino Guarino D, Graham TJA, Lengyel-Zhand Z, Schneider M, Tomita C, Lougee MG, Kim HJ, Pagar VV, Lee H, Hou C, Garcia BA, Petersson EJ, O'Shea J, Kotzbauer PT, Mathis CA, Lee VM, Luk KC, Mach RH. Kim HY, et al. Among authors: mathis ca. J Med Chem. 2023 Sep 14;66(17):12185-12202. doi: 10.1021/acs.jmedchem.3c00779. Epub 2023 Aug 31. J Med Chem. 2023. PMID: 37651366 Free PMC article.
Small-molecule PET Tracers for Imaging Proteinopathies.
Mathis CA, Lopresti BJ, Ikonomovic MD, Klunk WE. Mathis CA, et al. Semin Nucl Med. 2017 Sep;47(5):553-575. doi: 10.1053/j.semnuclmed.2017.06.003. Epub 2017 Jul 13. Semin Nucl Med. 2017. PMID: 28826526 Free PMC article. Review.
277 results