Pei Y - Search Results

1

Structural basis of β-glucopyranoside salicin recognition by a human bitter taste GPCR.

Wang X, Zhou C, Ao W, Wu L, Wu Y, Xu W, Liu S, Tan Q, Wang L, Zhao F, Liu J, Pei Y, Zhao S, Hua T. Wang X, et al. Among authors: pei y. Cell Rep. 2025 May 27;44(5):115604. doi: 10.1016/j.celrep.2025.115604. Epub 2025 Apr 21. Cell Rep. 2025. PMID: 40261795 Free article.

2

Structural basis for strychnine activation of human bitter taste receptor TAS2R46.

Xu W, Wu L, Liu S, Liu X, Cao X, Zhou C, Zhang J, Fu Y, Guo Y, Wu Y, Tan Q, Wang L, Liu J, Jiang L, Fan Z, Pei Y, Yu J, Cheng J, Zhao S, Hao X, Liu ZJ, Hua T. Xu W, et al. Among authors: pei y. Science. 2022 Sep 16;377(6612):1298-1304. doi: 10.1126/science.abo1633. Epub 2022 Sep 15. Science. 2022. PMID: 36108005

3

Bitter taste TAS2R14 activation by intracellular tastants and cholesterol.

Hu X, Ao W, Gao M, Wu L, Pei Y, Liu S, Wu Y, Zhao F, Sun Q, Liu J, Jiang L, Wang X, Li Y, Tan Q, Cheng J, Yang F, Yang C, Sun J, Hua T, Liu ZJ. Hu X, et al. Among authors: pei y. Nature. 2024 Jul;631(8020):459-466. doi: 10.1038/s41586-024-07569-9. Epub 2024 May 22. Nature. 2024. PMID: 38776963

4

Structural basis of stepwise proton sensing-mediated GPCR activation.

Yue X, Peng L, Liu S, Zhang B, Zhang X, Chang H, Pei Y, Li X, Liu J, Shui W, Wu L, Xu H, Liu ZJ, Hua T. Yue X, et al. Among authors: pei y. Cell Res. 2025 Jun;35(6):423-436. doi: 10.1038/s41422-025-01092-w. Epub 2025 Apr 11. Cell Res. 2025. PMID: 40211064 Free PMC article.

5

A large-scale curated and filterable dataset for cryo-EM foundation model pre-training.

Chen Q, Xu Z, Dai H, Shen Y, Zhang J, Liu Z, Pei Y, Yu J. Chen Q, et al. Among authors: pei y. Sci Data. 2025 Jun 7;12(1):960. doi: 10.1038/s41597-025-05179-2. Sci Data. 2025. PMID: 40483273 Free PMC article.

6

Dynamic algorithm for fitness function greatly improves the optimization efficiency of frequency selective surface for better design of radar.

Pei Y, Yu A, Qin J, Yi R, Yu X, Liu S, Zhu G, Zhu C, Hou X. Pei Y, et al. Sci Rep. 2022 Oct 5;12(1):16596. doi: 10.1038/s41598-022-20167-x. Sci Rep. 2022. PMID: 36198688 Free PMC article.

7

Discovery of thalidomide-based PROTAC small molecules as the highly efficient SHP2 degraders.

Yang X, Wang Z, Pei Y, Song N, Xu L, Feng B, Wang H, Luo X, Hu X, Qiu X, Feng H, Yang Y, Zhou Y, Li J, Zhou B. Yang X, et al. Among authors: pei y. Eur J Med Chem. 2021 Jun 5;218:113341. doi: 10.1016/j.ejmech.2021.113341. Epub 2021 Mar 11. Eur J Med Chem. 2021. PMID: 33780898

8

Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer.

Ding H, Pei Y, Li Y, Xu W, Mei L, Hou Z, Guang Y, Cao L, Li P, Cao H, Bian J, Chen K, Luo C, Zhou B, Zhang T, Li Z, Yang Y. Ding H, et al. Among authors: pei y. Bioorg Med Chem. 2021 Dec 15;52:116512. doi: 10.1016/j.bmc.2021.116512. Epub 2021 Nov 10. Bioorg Med Chem. 2021. PMID: 34801827

9

Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation.

Pei Y, Zhu P, Dang Y, Wu J, Yang X, Wan B, Liu JO, Yi Q, Yu L. Pei Y, et al. J Immunol. 2008 Jan 1;180(1):222-9. doi: 10.4049/jimmunol.180.1.222. J Immunol. 2008. PMID: 18097023 Free article.

10

IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI.

Zhu P, Jiang W, Cao L, Yu W, Pei Y, Yang X, Wan B, Liu JO, Yi Q, Yu L. Zhu P, et al. Among authors: pei y. J Immunol. 2010 Nov 1;185(9):5140-9. doi: 10.4049/jimmunol.1000849. Epub 2010 Sep 24. J Immunol. 2010. PMID: 20870937 Free article.

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