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Page 1
Clonal hematopoiesis-associated motoric deficits caused by monocyte-derived microglia accumulating in aging mice.
Kim JS, Trzebanski S, Shin SH, Schori L, Frumer Friedman GR, Ilani NC, Kadam A, Vicario R, Aust O, Bugaeva P, Piatek S, Ismajli LK, Hoffmann CJ, Scheller M, Boura-Halfon S, Kaushansky N, Golani O, Solomon A, Liu Z, Amann L, Böhm-Sturm P, Koch SP, Wenger N; Netherlands Brain Bank; Ginhoux F, Prinz M, Avraham R, Harms C, Geissmann F, Müller-Tidow C, Uderhardt S, Milenkovic I, Shlush L, Jung S. Kim JS, et al. Among authors: geissmann f. Cell Rep. 2025 May 27;44(5):115609. doi: 10.1016/j.celrep.2025.115609. Epub 2025 Apr 24. Cell Rep. 2025. PMID: 40279248 Free article.
A microglia clonal inflammatory disorder in Alzheimer's Disease.
Vicario R, Fragkogianni S, Weber L, Lazarov T, Hu Y, Hayashi SY, Craddock BP, Socci ND, Alberdi A, Baako A, Ay O, Ogishi M, Lopez-Rodrigo E, Kappagantula R, Viale A, Iacobuzio-Donahue CA, Zhou T, Ransohoff RM, Chesworth R; Netherlands Brain Bank; Abdel-Wahab O, Boisson B, Elemento O, Casanova JL, Miller WT, Geissmann F. Vicario R, et al. Among authors: geissmann f. bioRxiv [Preprint]. 2024 Aug 3:2024.01.25.577216. doi: 10.1101/2024.01.25.577216. bioRxiv. 2024. Update in: Elife. 2025 Mar 14;13:RP96519. doi: 10.7554/eLife.96519. PMID: 38328106 Free PMC article. Updated. Preprint.
Role of clonal inflammatory microglia in histiocytosis-associated neurodegeneration.
Vicario R, Fragkogianni S, Pokrovskii M, Meyer C, Lopez-Rodrigo E, Hu Y, Ogishi M, Alberdi A, Baako A, Ay O, Plu I, Sazdovitch V, Heritier S, Cohen-Aubart F, Shor N, Miyara M, Nguyen-Khac F, Viale A, Idbaih A, Amoura Z, Rosenblum MK, Zhang H, Karnoub ER, Sashittal P, Jakatdar A, Iacobuzio-Donahue CA, Abdel-Wahab O, Tabar V, Socci ND, Elemento O, Diamond EL, Boisson B, Casanova JL, Seilhean D, Haroche J, Donadieu J, Geissmann F. Vicario R, et al. Among authors: geissmann f. Neuron. 2025 Apr 2;113(7):1065-1081.e13. doi: 10.1016/j.neuron.2025.02.007. Epub 2025 Mar 12. Neuron. 2025. PMID: 40081365 Free article.
Mechanism of neurodegeneration mediated by clonal inflammatory microglia.
Vicario R, Fragkogianni S, Pokrovskii M, Mayer C, Lopez-Rodrigo E, Hu Y, Ogishi M, Alberdi A, Baako A, Ay O, Plu I, Sazdovitch V, Heritier S, Cohen-Aubart F, Shor N, Miyara M, Nguyen-Khac F, Viale A, Idbaih A, Amoura Z, Rosenblum MK, Zhang H, Karnoub ER, Sashittal P, Jakatdar A, Iacobuzio-Donahue CA, Abdel-Wahab O, Tabar V, Socci ND, Elemento O, Diamond EL, Boisson B, Casanova JL, Seilhean D, Haroche J, Donadieu J, Geissmann F. Vicario R, et al. Among authors: geissmann f. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.605867. doi: 10.1101/2024.07.30.605867. bioRxiv. 2024. PMID: 39131366 Free PMC article. Preprint.
Hematopoietic Somatic Mosaicism Is Associated With an Increased Risk of Postoperative Atrial Fibrillation.
Ninni S, Dombrowicz D, Kuznetsova T, Vicario R, Gao V, Molendi-Coste O, Haas J, Woitrain E, Coisne A, Neele AE, Prange K, Willemsen L, Aghezzaf S, Fragkogianni S, Tazibet A, Pineau L, White JR, Eeckhoute J, Koussa M, Dubrulle H, Juthier F, Soquet J, Vincentelli A, Edme JL, de Winther M, Geissmann F, Staels B, Montaigne D. Ninni S, et al. Among authors: geissmann f. J Am Coll Cardiol. 2023 Apr 4;81(13):1263-1278. doi: 10.1016/j.jacc.2023.01.036. J Am Coll Cardiol. 2023. PMID: 36990546 Free PMC article.
Breast Cancer Macrophage Heterogeneity and Self-renewal are Determined by Spatial Localization.
Ben-Chetrit N, Niu X, Sotelo J, Swett AD, Rajasekhar VK, Jiao MS, Stewart CM, Bhardwaj P, Kottapalli S, Ganesan S, Loyher PL, Potenski C, Hannuna A, Brown KA, Iyengar NM, Giri DD, Lowe SW, Healey JH, Geissmann F, Sagi I, Joyce JA, Landau DA. Ben-Chetrit N, et al. Among authors: geissmann f. bioRxiv [Preprint]. 2023 Oct 27:2023.10.24.563749. doi: 10.1101/2023.10.24.563749. bioRxiv. 2023. PMID: 37961223 Free PMC article. Preprint.
Early life high fructose impairs microglial phagocytosis and neurodevelopment.
Wang Z, Lipshutz A, Martínez de la Torre C, Trzeciak AJ, Liu ZL, Miranda IC, Lazarov T, Codo AC, Romero-Pichardo JE, Nair A, Schild T, Saitz Rojas W, Saavedra PHV, Baako AK, Fadojutimi K, Downey MS, Geissmann F, Faraco G, Gan L, Etchegaray JI, Lucas CD, Tanasova M, Parkhurst CN, Zeng MY, Keshari KR, Perry JSA. Wang Z, et al. Among authors: geissmann f. Nature. 2025 Jun 11:10.1038/s41586-025-09098-5. doi: 10.1038/s41586-025-09098-5. Online ahead of print. Nature. 2025. PMID: 40500435 Free PMC article.
A microglia clonal inflammatory disorder in Alzheimer's disease.
Vicario R, Fragkogianni S, Weber L, Lazarov T, Hu Y, Hayashi SY, Craddock B, Socci ND, Alberdi A, Baako A, Ay O, Ogishi M, Lopez-Rodrigo E, Kappagantula R, Viale A, Iacobuzio-Donahue CA, Zhou T, Ransohoff RM, Chesworth R; Netherlands Brain Bank; Abdel-Wahab O, Boisson B, Elemento O, Casanova JL, Miller WT, Geissmann F. Vicario R, et al. Among authors: geissmann f. Elife. 2025 Mar 14;13:RP96519. doi: 10.7554/eLife.96519. Elife. 2025. PMID: 40085681 Free PMC article.
ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.
Guillet S, Lazarov T, Jordan N, Boisson B, Tello M, Craddock B, Zhou T, Nishi C, Bareja R, Yang H, Rieux-Laucat F, Fregel Lorenzo RI, Dyall SD, Isenberg D, D'Cruz D, Lachmann N, Elemento O, Viale A, Socci ND, Abel L, Nagata S, Huse M, Miller WT, Casanova JL, Geissmann F. Guillet S, et al. Among authors: geissmann f. Elife. 2024 Nov 21;13:RP96085. doi: 10.7554/eLife.96085. Elife. 2024. PMID: 39570652 Free PMC article.
Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads.
Thalhammer J, Jeziorski E, Marec-Bérard P, Barkaoui MA, Pagnier A, Rohrlich PS, Chevallier A, Carausu L, Aladjidi N, Rigaud C, Leruste A, Azarnoush S, Lauvray T, Le Louet S, Gandemer V, Treguier P, Mansuy L, Pasquet M, Olivier L, Rome A, Saultier P, Isfan F, Renard C, Li Thiao Te V, Salmon A, Blanc L, Abou Chahla W, Lambilliotte A, Stephan JL, Geissmann F, Lejeune J, Mallebranche C, Reguerre Y, Grain A, Thomas C, Hélias-Rodzewicz Z, Moshous D, Fenneteau O, Coulomb-L'Hermine A, Lapillonne H, de Saint-Basile G, Emile JF, Héritier S, Donadieu J. Thalhammer J, et al. Among authors: geissmann f. Blood. 2025 Mar 6;145(10):1061-1073. doi: 10.1182/blood.2024025625. Blood. 2025. PMID: 39486044 Free article.
153 results