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Three-dimensional genome landscape of primary human cancers.
Yost KE, Zhao Y, Hung KL, Zhu K, Xu D, Corces MR, Shams S, Louie BH, Sarmashghi S, Sundaram L, Luebeck J, Clarke S, Doane AS, Granja JM, Choudhry H, Imieliński M, Cherniack AD, Khurana E, Bafna V, Felau I, Zenklusen JC, Laird PW, Curtis C; Cancer Genome Atlas Analysis Network; Greenleaf WJ, Chang HY. Yost KE, et al. Among authors: zhu k. Nat Genet. 2025 May;57(5):1189-1200. doi: 10.1038/s41588-025-02188-0. Epub 2025 May 12. Nat Genet. 2025. PMID: 40355593 Free PMC article.
Breakage fusion bridge cycles drive high oncogene number with moderate intratumoural heterogeneity.
Raeisi Dehkordi S, Wong IT, Ni J, Luebeck J, Zhu K, Prasad G, Krockenberger L, Xu G, Chowdhury B, Rajkumar U, Caplin A, Muliaditan D, Gnanasekar A, Coruh C, Jin Q, Turner K, Teo SX, Pang AWC, Alexandrov LB, Chua CEL, Furnari FB, Maciejowski J, Paulson TG, Law JA, Chang HY, Yue F, DasGupta R, Zhao J, Mischel PS, Bafna V. Raeisi Dehkordi S, et al. Among authors: zhu k. Nat Commun. 2025 Feb 10;16(1):1497. doi: 10.1038/s41467-025-56670-8. Nat Commun. 2025. PMID: 39929823 Free PMC article.
Inhibition of human-HPV hybrid ecDNA enhancers reduces oncogene expression and tumor growth in oropharyngeal cancer.
Nakagawa T, Luebeck J, Zhu K, Lange JT, Sasik R, Phillips C, Sadat S, Javadzadeh S, Yang Q, Monther A, Fassardi S, Wang A, Pestonjamasp K, Rosenthal B, Fisch KM, Mischel P, Bafna V, Califano JA. Nakagawa T, et al. Among authors: zhu k. Nat Commun. 2025 Mar 26;16(1):2964. doi: 10.1038/s41467-025-57447-9. Nat Commun. 2025. PMID: 40140353 Free PMC article.
6,625 results