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Acute Effects of Riluzole and Retigabine on Axonal Excitability in Patients With Amyotrophic Lateral Sclerosis: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial.
Kovalchuk MO, Heuberger JAAC, Sleutjes BTHM, Ziagkos D, van den Berg LH, Ferguson TA, Franssen H, Groeneveld GJ. Kovalchuk MO, et al. Among authors: groeneveld gj. Clin Pharmacol Ther. 2018 Dec;104(6):1136-1145. doi: 10.1002/cpt.1096. Epub 2018 Jun 19. Clin Pharmacol Ther. 2018. PMID: 29672831 Clinical Trial.
DNL104, a Centrally Penetrant RIPK1 Inhibitor, Inhibits RIP1 Kinase Phosphorylation in a Randomized Phase I Ascending Dose Study in Healthy Volunteers.
Grievink HW, Heuberger JAAC, Huang F, Chaudhary R, Birkhoff WAJ, Tonn GR, Mosesova S, Erickson R, Moerland M, Haddick PCG, Scearce-Levie K, Ho C, Groeneveld GJ. Grievink HW, et al. Among authors: groeneveld gj. Clin Pharmacol Ther. 2020 Feb;107(2):406-414. doi: 10.1002/cpt.1615. Epub 2019 Sep 25. Clin Pharmacol Ther. 2020. PMID: 31437302 Clinical Trial.
TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects.
de Cuba CMKE, de Goede AA, Klaassen ES, Otto ME, Doll RJ, Kim J, Demitrack MA, Chen R, Groeneveld GJ, Heuberger JAAC. de Cuba CMKE, et al. Among authors: groeneveld gj. Clin Pharmacol Ther. 2025 Mar;117(3):787-797. doi: 10.1002/cpt.3521. Epub 2024 Dec 6. Clin Pharmacol Ther. 2025. PMID: 39641417 Free PMC article. Clinical Trial.
Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.
Ruijs TQ, de Cuba CMKE, Heuberger JAAC, Hutchison J, Bold J, Grønnebæk TS, Jensen KG, Chin E, Quiroz JA, Petersen TK, Flagstad P, de Kam ML, van Esdonk MJ, Klaassen E, Doll RJ, Koopmans IW, de Goede AA, Aulin LBS, Pedersen TH, Groeneveld GJ. Ruijs TQ, et al. Among authors: groeneveld gj. Clin Pharmacol Ther. 2025 Mar;117(3):768-778. doi: 10.1002/cpt.3516. Epub 2024 Dec 9. Clin Pharmacol Ther. 2025. PMID: 39651850 Free PMC article. Clinical Trial.
154 results