Atkin JD - Search Results

1

Pathological forms of TDP-43 in amyotrophic lateral sclerosis (ALS) promote aberrant telomere elongation.

Konopka A, Jamali MS, Fowler M, Mehta P, Parakh S, Takalloo Z, Farzana F, Mumtaz N, Hunter J, Shadfar S, Rogers ML, Atkin JD. Konopka A, et al. Among authors: atkin jd. Biochim Biophys Acta Mol Basis Dis. 2025 May 14;1871(7):167906. doi: 10.1016/j.bbadis.2025.167906. Online ahead of print. Biochim Biophys Acta Mol Basis Dis. 2025. PMID: 40379219 Free article.

2

Redox regulation in amyotrophic lateral sclerosis.

Parakh S, Spencer DM, Halloran MA, Soo KY, Atkin JD. Parakh S, et al. Among authors: atkin jd. Oxid Med Cell Longev. 2013;2013:408681. doi: 10.1155/2013/408681. Epub 2013 Feb 25. Oxid Med Cell Longev. 2013. PMID: 23533690 Free PMC article. Review.

3

ALS-associated TDP-43 induces endoplasmic reticulum stress, which drives cytoplasmic TDP-43 accumulation and stress granule formation.

Walker AK, Soo KY, Sundaramoorthy V, Parakh S, Ma Y, Farg MA, Wallace RH, Crouch PJ, Turner BJ, Horne MK, Atkin JD. Walker AK, et al. Among authors: atkin jd. PLoS One. 2013 Nov 29;8(11):e81170. doi: 10.1371/journal.pone.0081170. eCollection 2013. PLoS One. 2013. PMID: 24312274 Free PMC article.

4

The role of s-nitrosylation and s-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration.

Halloran M, Parakh S, Atkin JD. Halloran M, et al. Among authors: atkin jd. Int J Cell Biol. 2013;2013:797914. doi: 10.1155/2013/797914. Epub 2013 Nov 18. Int J Cell Biol. 2013. PMID: 24348565 Free PMC article. Review.

5

Novel roles for protein disulphide isomerase in disease states: a double edged sword?

Parakh S, Atkin JD. Parakh S, et al. Among authors: atkin jd. Front Cell Dev Biol. 2015 May 21;3:30. doi: 10.3389/fcell.2015.00030. eCollection 2015. Front Cell Dev Biol. 2015. PMID: 26052512 Free PMC article. Review.

6

Rab1-dependent ER-Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS.

Soo KY, Halloran M, Sundaramoorthy V, Parakh S, Toth RP, Southam KA, McLean CA, Lock P, King A, Farg MA, Atkin JD. Soo KY, et al. Among authors: atkin jd. Acta Neuropathol. 2015 Nov;130(5):679-97. doi: 10.1007/s00401-015-1468-2. Epub 2015 Aug 23. Acta Neuropathol. 2015. PMID: 26298469

7

The Unfolded Protein Response and the Role of Protein Disulfide Isomerase in Neurodegeneration.

Perri ER, Thomas CJ, Parakh S, Spencer DM, Atkin JD. Perri ER, et al. Among authors: atkin jd. Front Cell Dev Biol. 2016 Jan 8;3:80. doi: 10.3389/fcell.2015.00080. eCollection 2015. Front Cell Dev Biol. 2016. PMID: 26779479 Free PMC article. Review.

8

Efficacy of peptide nucleic acid and selected conjugates against specific cellular pathologies of amyotrophic lateral sclerosis.

Browne EC, Parakh S, Duncan LF, Langford SJ, Atkin JD, Abbott BM. Browne EC, et al. Among authors: atkin jd. Bioorg Med Chem. 2016 Apr 1;24(7):1520-7. doi: 10.1016/j.bmc.2016.02.022. Epub 2016 Feb 18. Bioorg Med Chem. 2016. PMID: 26935939

9

Protein folding alterations in amyotrophic lateral sclerosis.

Parakh S, Atkin JD. Parakh S, et al. Among authors: atkin jd. Brain Res. 2016 Oct 1;1648(Pt B):633-649. doi: 10.1016/j.brainres.2016.04.010. Epub 2016 Apr 7. Brain Res. 2016. PMID: 27064076 Review.

10

Protein Disulphide Isomerases: emerging roles of PDI and ERp57 in the nervous system and as therapeutic targets for ALS.

Perri E, Parakh S, Atkin J. Perri E, et al. Expert Opin Ther Targets. 2017 Jan;21(1):37-49. doi: 10.1080/14728222.2016.1254197. Epub 2016 Nov 25. Expert Opin Ther Targets. 2017. PMID: 27786579 Review.

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