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A mouse model of Jansen's metaphyseal chondrodysplasia for investigating disease mechanisms and candidate therapeutics.
Höppner J, Firat D, Parvez-Khan M, Reyes M, Hanna P, Yadav PS, Dean T, Ramos-Torres KM, Brugarolas P, Collins MT, Wein MN, Liu S, Gellman SH, Schipani E, Kronenberg HM, Gardella TJ, Jüppner H. Höppner J, et al. Among authors: wein mn. Proc Natl Acad Sci U S A. 2025 Jun 10;122(23):e2500176122. doi: 10.1073/pnas.2500176122. Epub 2025 Jun 2. Proc Natl Acad Sci U S A. 2025. PMID: 40455993
Regulation of Bone Remodeling by Parathyroid Hormone.
Wein MN, Kronenberg HM. Wein MN, et al. Cold Spring Harb Perspect Med. 2018 Aug 1;8(8):a031237. doi: 10.1101/cshperspect.a031237. Cold Spring Harb Perspect Med. 2018. PMID: 29358318 Free PMC article. Review.
Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling.
Nishimori S, O'Meara MJ, Castro CD, Noda H, Cetinbas M, da Silva Martins J, Ayturk U, Brooks DJ, Bruce M, Nagata M, Ono W, Janton CJ, Bouxsein ML, Foretz M, Berdeaux R, Sadreyev RI, Gardella TJ, Jüppner H, Kronenberg HM, Wein MN. Nishimori S, et al. Among authors: wein mn. J Clin Invest. 2019 Dec 2;129(12):5187-5203. doi: 10.1172/JCI130126. J Clin Invest. 2019. PMID: 31430259 Free PMC article.
SIKs control osteocyte responses to parathyroid hormone.
Wein MN, Liang Y, Goransson O, Sundberg TB, Wang J, Williams EA, O'Meara MJ, Govea N, Beqo B, Nishimori S, Nagano K, Brooks DJ, Martins JS, Corbin B, Anselmo A, Sadreyev R, Wu JY, Sakamoto K, Foretz M, Xavier RJ, Baron R, Bouxsein ML, Gardella TJ, Divieti-Pajevic P, Gray NS, Kronenberg HM. Wein MN, et al. Nat Commun. 2016 Oct 19;7:13176. doi: 10.1038/ncomms13176. Nat Commun. 2016. PMID: 27759007 Free PMC article.
HDAC5 controls MEF2C-driven sclerostin expression in osteocytes.
Wein MN, Spatz J, Nishimori S, Doench J, Root D, Babij P, Nagano K, Baron R, Brooks D, Bouxsein M, Pajevic PD, Kronenberg HM. Wein MN, et al. J Bone Miner Res. 2015 Mar;30(3):400-11. doi: 10.1002/jbmr.2381. J Bone Miner Res. 2015. PMID: 25271055 Free PMC article.
64 results