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Page 1
Subcutaneous blinatumomab in adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: post-hoc safety and activity analysis from a multicentre, single-arm, phase 1/2 trial.
Jabbour E, Lussana F, Martínez-Sánchez P, Torrent A, Rifón JJ, Agrawal V, Tormo M, Cassaday RD, Cluzeau T, Huguet F, Papayannidis C, Hernández-Rivas JM, Rijneveld A, Fleming S, Vucinic V, Böll B, Ikezoe T, Abdul-Hay M, Savoie ML, Schuh AC, Berthon C, Schwartz S, Chiaretti S, Yuda J, Miyazaki T, González-Campos J, Chen Y, Wong H, Choudhry J, Zugmaier G, Guest E, Gordon P, Kantarjian H. Jabbour E, et al. Among authors: hernandez rivas jm. Lancet Haematol. 2025 Jul;12(7):e529-e541. doi: 10.1016/S2352-3026(25)00144-9. Epub 2025 Jun 15. Lancet Haematol. 2025. PMID: 40532723 Clinical Trial.
Optimizing Patient Registries for Regulatory Decision Making - Key Learnings From an HMA/EMA Multistakeholder Workshop.
Plueschke K, Jonker C, Kankanen H, Vetter T, Sepodes B, Naehrlich L, Hillert J, Crane G, Straus S, Foggi P, Martin S, Kyriakopoulou C, Mol P, Day F, Breen K, Bennett N, de Lemus Belmonte M, Bennett S, Verpillat P, Roes KCB, Cochino A, Schaefer F, Hernández-Rivas JM, McGettigan P, Arlett P. Plueschke K, et al. Among authors: hernandez rivas jm. Clin Pharmacol Ther. 2025 Jun 2. doi: 10.1002/cpt.3733. Online ahead of print. Clin Pharmacol Ther. 2025. PMID: 40457718 Review.
NOTCH1 signaling is dysregulated by loss of the deubiquitinase USP28 with del(11q), uncovering USP28 inhibition as novel therapeutic target in CLL.
Ehrmann AS, Quijada-Álamo M, Close V, Guo M, Carracoi V, Pérez-Carretero C, Corchete LA, Friedrich T, Giaimo BD, Yosifov DY, Bloehdorn J, Rodríguez-Sánchez A, Tausch E, Schneider C, Döhner H, Kietzmann T, Borggrefe T, Stilgenbauer S, Oswald F, Hernández-Rivas JM, Mertens D. Ehrmann AS, et al. Among authors: hernandez rivas jm. Leukemia. 2025 Jun 2. doi: 10.1038/s41375-025-02632-4. Online ahead of print. Leukemia. 2025. PMID: 40456839
Examining the Effects of the RUNX1 p.Leu43Ser Variant on FPD/AML Phenotypes Using a CRISPR/Cas9-Generated Knock-In Murine Model.
Marin-Quilez A, García-Tuñón I, Benito R, Ordoñez JL, Díaz-Ajenjo L, Lama-Villanueva A, Guerrero C, Pérez-Losada J, González-Porras JR, Hernández-Rivas JM, Del Rey M, Bastida JM. Marin-Quilez A, et al. Among authors: hernandez rivas jm. Biomolecules. 2025 May 12;15(5):708. doi: 10.3390/biom15050708. Biomolecules. 2025. PMID: 40427601 Free PMC article.
Comparability of external and internal control patients for the prospective randomized HOVON-103 trial in older AML patients.
Hermans SJF, Versluis J, van Werkhoven ED, van Norden Y, Janssen JJWM, Huls GA, Pabst T, Breems DA, Berkx E, Dinmohamed AG, Huijgens PC, Sträng E, Hernández Rivas JM, Sobas M, Ayala Diaz R, Martinez Lopez J, Metzeler KH, Haferlach T, Thiede C, Uyl-de Groot CA, Bullinger L, Löwenberg B, Ossenkoppele GJ, Pignatti F, Cornelissen JJ. Hermans SJF, et al. Among authors: hernandez rivas jm. Br J Haematol. 2025 May 26. doi: 10.1111/bjh.20185. Online ahead of print. Br J Haematol. 2025. PMID: 40419286
ATM aberrations in chronic lymphocytic leukemia: del(11q) rather than ATM mutations is an adverse-prognostic biomarker.
Thorvaldsdottir B, Mansouri L, Sutton LA, Nadeu F, Meggendorfer M, Parker H, Brieghel C, Laidou S, Moia R, Rossi D, Kotaskova J, Delgado J, Rodríguez-Vicente AE, Benito R, Rigolin GM, Bonfiglio S, Scarfò L, Mattsson M, Davis Z, Baliakas P, Rapado I, Miras F, Martinez-Lopez J, de la Serna J, Hernández Rivas JM, Larráyoz MJ, Calasanz MJ, Smedby KE, Espinet B, Puiggros A, Bullinger L, Bosch F, Tazón-Vega B, Baran-Marszak F, Oscier D, Nguyen-Khac F, Zenz T, Terol MJ, Cuneo A, Hernández-Sánchez M, Pospisilova S, Gaidano G, Niemann CU, Campo E, Strefford JC, Ghia P, Stamatopoulos K, Rosenquist R. Thorvaldsdottir B, et al. Among authors: hernandez rivas jm. Leukemia. 2025 Jul;39(7):1650-1660. doi: 10.1038/s41375-025-02615-5. Epub 2025 Apr 24. Leukemia. 2025. PMID: 40275070 Free PMC article.
SAMHD1 dysfunction impairs DNA damage response and increases sensitivity to PARP inhibition in chronic lymphocytic leukemia.
Rodríguez-Sánchez A, Quijada-Álamo M, Pérez-Carretero C, Herrero AB, Arroyo-Barea A, Dávila-Valls J, Rubio A, García de Coca A, Benito-Sánchez R, Rodríguez-Vicente AE, Hernández-Rivas JM, Hernández-Sánchez M. Rodríguez-Sánchez A, et al. Among authors: hernandez rivas jm. Sci Rep. 2025 Mar 26;15(1):10446. doi: 10.1038/s41598-025-93629-7. Sci Rep. 2025. PMID: 40140468 Free PMC article.
Sex Differences in Gut Microbiota and Their Relation to Arterial Stiffness (MIVAS Study).
Salvado R, Lugones-Sánchez C, Santos-Minguez S, González-Sánchez S, Quesada JA, Benito R, Rodríguez-Sánchez E, Gómez-Marcos MA, Guimarães-Cunha P, Hernandez-Rivas JM, Mira A, García-Ortiz L, Mivas Investigators. Salvado R, et al. Among authors: hernandez rivas jm. Nutrients. 2024 Dec 27;17(1):53. doi: 10.3390/nu17010053. Nutrients. 2024. PMID: 39796488 Free PMC article.
Preferential Genetic Pathways Lead to Relapses in Adult B-Cell Acute Lymphoblastic Leukemia.
Navas-Acosta J, Hernández-Sánchez A, González T, Villaverde Ramiro Á, Santos S, Miguel C, Ribera J, Granada I, Morgades M, Sánchez R, Such E, Barrena S, Ciudad J, Dávila J, de Las Heras N, García-de Coca A, Labrador J, Queizán JA, Martín S, Orfao A, Ribera JM, Benito R, Hernández-Rivas JM. Navas-Acosta J, et al. Among authors: hernandez rivas jm. Cancers (Basel). 2024 Dec 17;16(24):4200. doi: 10.3390/cancers16244200. Cancers (Basel). 2024. PMID: 39766099 Free PMC article.
194 results