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Multi-omic spatial profiling reveals the unique SARS-CoV-2 lung microenvironment and collagen VI as a predictive biomarker in severe COVID-19.
Fennell É, Taylor GS, Leahy CI, Ross AM, Reynolds G, Perry T, Youd E, Skidmore J, Ramzi R, Darwish R, Hunter KJ, Willcox BE, Jermann P, Arif Jahangir C, Rahman A, Gallagher WM, Nikulina N, Ben Cheikh B, Braubach O, Mayer AT, Young LS, Grammatopoulos D, Faustini S, Richter A, Dowell AC, Venith T, Thein OS, Parekh D, Belchamber KBR, Thickett DR, Scott A, Attanoos R, Mundo L, Lazzi S, Leoncini L, Leopold G, Steven N, Marie J, Sand B, Karsdal MA, Julie Leeming D, Dojcinov S, Culhane A, Murray PG, Pugh MR. Fennell É, et al. Among authors: culhane a. Eur Respir J. 2025 Jun 5:2301699. doi: 10.1183/13993003.01699-2023. Online ahead of print. Eur Respir J. 2025. PMID: 40473310
Health diplomacy in action: The cancer legacy of the Good Friday Agreement.
Lawler M, Sullivan R, Abou-Alfa GK, McCloskey K, Keatley D, Feighan J, Dahut W, Mulroe E, Ladner R, Genead M, Lowery M, Gulley JL, Scott CJ, Longley DB, Culhane A, Gallagher WM, Orr N, Chanock SJ, Gopal S. Lawler M, et al. Among authors: culhane a. J Cancer Policy. 2023 Dec;38:100448. doi: 10.1016/j.jcpo.2023.100448. Epub 2023 Oct 14. J Cancer Policy. 2023. PMID: 37839622 Free article.
Learning and teaching biological data science in the Bioconductor community.
Drnevich J, Tan FJ, Almeida-Silva F, Castelo R, Culhane AC, Davis S, Doyle MA, Geistlinger L, Ghazi AR, Holmes S, Lahti L, Mahmoud A, Nishida K, Ramos M, Rue-Albrecht K, Shih DJH, Gatto L, Soneson C. Drnevich J, et al. Among authors: culhane ac. PLoS Comput Biol. 2025 Apr 22;21(4):e1012925. doi: 10.1371/journal.pcbi.1012925. eCollection 2025 Apr. PLoS Comput Biol. 2025. PMID: 40261894 Free PMC article.
Learning and teaching biological data science in the Bioconductor community.
Drnevich J, Tan FJ, Almeida-Silva F, Castelo R, Culhane AC, Davis S, Doyle MA, Geistlinger L, Ghazi AR, Holmes S, Lahti L, Mahmoud A, Nishida K, Ramos M, Rue-Albrecht K, Shih DJ, Gatto L, Soneson C. Drnevich J, et al. Among authors: culhane ac. ArXiv [Preprint]. 2025 Mar 11:arXiv:2410.01351v2. ArXiv. 2025. Update in: PLoS Comput Biol. 2025 Apr 22;21(4):e1012925. doi: 10.1371/journal.pcbi.1012925. PMID: 40160449 Free PMC article. Updated. Preprint.
An Allele of the MTHFR one-carbon metabolism gene predicts severity of COVID-19.
Petrova B, Syphurs C, Culhane AJ, Chen J, Chen E, Cotsapas C, Esserman D, Montgomery R, Kleinstein S, Smolen K, Mendez K; IMPACC Network; Lasky-Su J, Steen H, Levy O, Diray-Arce J, Kanarek N. Petrova B, et al. Among authors: culhane aj. medRxiv [Preprint]. 2025 Mar 3:2025.02.28.25323089. doi: 10.1101/2025.02.28.25323089. medRxiv. 2025. PMID: 40093216 Free PMC article. Preprint.
The 1+Million Genomes Minimal Dataset for Cancer.
Riba M, Sala C, Culhane AC, Flobak Å, Patocs A, Boye K, Plevova K, Pospíšilová Š, Gandolfi G, Morelli MJ, Bucci G, Edsjö A, Lassen U, Al-Shahrour F, Lopez-Bigas N, Hovland R, Cuppen E, Valencia A, Poirel HA, Rosenquist R, Scollen S, Arenas Marquez J, Belien J, De Nicolo A, De Maria R, Torrents D, Tonon G. Riba M, et al. Among authors: culhane ac. Nat Genet. 2024 May;56(5):733-736. doi: 10.1038/s41588-024-01721-x. Nat Genet. 2024. PMID: 38702538 No abstract available.
Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model.
Wang Y, Cho JW, Kastrunes G, Buck A, Razimbaud C, Culhane AC, Sun J, Braun DA, Choueiri TK, Wu CJ, Jones K, Nguyen QD, Zhu Z, Wei K, Zhu Q, Signoretti S, Freeman GJ, Hemberg M, Marasco WA. Wang Y, et al. Among authors: culhane ac. iScience. 2024 Jan 15;27(2):108879. doi: 10.1016/j.isci.2024.108879. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327771 Free PMC article.
111 results