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152 results

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Page 1
Inherited mitochondrial genetics as a predictor of immune checkpoint inhibition efficacy in melanoma.
Monson KR, Ferguson R, Handzlik JE, Morales L, Xiong J, Chat V, Dagayev S, Khodadadi-Jamayran A, Simpson D, Kazlow E, Bunis A, Sreenivasaiah C, Ibrahim M, Voloshyna I, Ouwerkerk W, Luiten RM, Capone M, Madonna G, Lu Y, Shao Y, Pavlick A, Krogsgaard M, Mehnert J, Tang H, Dolfi S, Tenney D, Haanen JBAG, Gajewski TF, Hodi FS, Flaherty KT, Couts K, Robinson W, Puzanov I, Ernstoff MS, Rahma O, Postow M, Sullivan RJ, Luke JJ, Ascierto PA; IO-GEM Consortium; Osman I, Kirchhoff T. Monson KR, et al. Among authors: kirchhoff t. Nat Med. 2025 Jun 5. doi: 10.1038/s41591-025-03699-3. Online ahead of print. Nat Med. 2025. PMID: 40473950
Germline immunomodulatory expression quantitative trait loci (ieQTLs) associated with immune-related toxicity from checkpoint inhibition.
Ferguson R, Chat V, Morales L, Simpson D, Monson KR, Cohen E, Zusin S, Madonna G, Capone M, Simeone E, Pavlick A, Luke JJ, Gajewski TF, Osman I, Ascierto P, Weber J, Kirchhoff T. Ferguson R, et al. Among authors: kirchhoff t. Eur J Cancer. 2023 Aug;189:112923. doi: 10.1016/j.ejca.2023.05.011. Epub 2023 May 18. Eur J Cancer. 2023. PMID: 37301715 Free PMC article.
Tyrosine Protein Kinase SYK-Related Gene Signature in Baseline Immune Cells Associated with Adjuvant Immunotherapy-Induced Immune-Related Adverse Events in Melanoma.
Monson KR, Ferguson R, Handzlik JE, Xiong J, Dagayev S, Morales L, Chat V, Bunis A, Sreenivasaiah C, Dolfi S, Tenney DJ, Shao Y, Osman I, Weber JS, Kirchhoff T. Monson KR, et al. Among authors: kirchhoff t. Clin Cancer Res. 2024 Oct 1;30(19):4412-4423. doi: 10.1158/1078-0432.CCR-24-0900. Clin Cancer Res. 2024. PMID: 39115425
Kinase Insert Domain Receptor Q472H Pathogenic Germline Variant Impacts Melanoma Tumor Growth and Patient Treatment Outcomes.
Ibrahim M, Illa-Bochaca I, Fa'ak F, Monson KR, Ferguson R, Lyu C, Vega-Saenz de Miera E, Johannet P, Chou M, Mastroianni J, Darvishian F, Kirchhoff T, Zhong J, Krogsgaard M, Osman I. Ibrahim M, et al. Among authors: kirchhoff t. Cancers (Basel). 2023 Dec 19;16(1):18. doi: 10.3390/cancers16010018. Cancers (Basel). 2023. PMID: 38201446 Free PMC article.
Phase II clinical and immune correlate study of adjuvant nivolumab plus ipilimumab for high-risk resected melanoma.
Khushalani NI, Vassallo M, Goldberg JD, Eroglu Z, Kim Y, Cao B, Ferguson R, Monson KR, Kirchhoff T, Amato CM, Burke P, Strange A, Monk E, Gibney GT, Kudchadkar R, Markowitz J, Brohl AS, Pavlick A, Richards A, Woods DM, Weber J. Khushalani NI, et al. Among authors: kirchhoff t. J Immunother Cancer. 2022 Nov;10(11):e005684. doi: 10.1136/jitc-2022-005684. J Immunother Cancer. 2022. PMID: 36450385 Free PMC article. Clinical Trial.
Perspectives in Immunotherapy: meeting report from Immunotherapy Bridge (Naples, November 30th-December 1st, 2022).
Ascierto PA, Avallone A, Bifulco C, Bracarda S, Brody JD, Emens LA, Ferris RL, Formenti SC, Hamid O, Johnson DB, Kirchhoff T, Klebanoff CA, Lesinski GB, Monette A, Neyns B, Odunsi K, Paulos CM, Powell DJ Jr, Rezvani K, Segal BH, Singh N, Sullivan RJ, Fox BA, Puzanov I. Ascierto PA, et al. Among authors: kirchhoff t. J Transl Med. 2023 Jul 20;21(1):488. doi: 10.1186/s12967-023-04329-7. J Transl Med. 2023. PMID: 37475035 Free PMC article.
Advances in the understanding and therapeutic manipulation of cancer immune responsiveness: a Society for Immunotherapy of Cancer (SITC) review.
Cesano A, Augustin R, Barrea L, Bedognetti D, Bruno TC, Carturan A, Hammer C, Ho WS, Kather JN, Kirchhoff T, Lu RO, McQuade J, Najjar YG, Pietrobon V, Ruella M, Shen R, Soldati L, Spencer C, Betof Warner A, Warren S, Ziv E, Marincola FM. Cesano A, et al. Among authors: kirchhoff t. J Immunother Cancer. 2025 Jan 16;13(1):e008876. doi: 10.1136/jitc-2024-008876. J Immunother Cancer. 2025. PMID: 39824527 Free PMC article. Review.
152 results