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Synthesis of Ethylphosphonate Curcumin Mimics: Substituents Allow Switching Between Cytotoxic and Cytoprotective Activities.
Romanucci V, Pagano R, Koeberle SC, Koeberle A, Hoang MB, Di Gaetano S, Capasso D, Sciacca MFM, Lanza V, Tempra C, Lolicato F, Zarrelli A, Milardi D, Di Fabio G. Romanucci V, et al. Among authors: sciacca mfm. Antioxidants (Basel). 2025 Mar 29;14(4):412. doi: 10.3390/antiox14040412. Antioxidants (Basel). 2025. PMID: 40298666 Free PMC article.
Acute targeting of N-terminal tau protein has long-lasting beneficial effects in Tg2576 APP/Aβ mouse model by reducing cognitive impairment, cerebral Aβ-amyloidosis, synaptic remodeling and microgliosis later in life.
Latina V, De Introna M, Malerba F, Florio R, Balzamino BO, Di Natale G, Sciacca MFM, Pappalardo G, Micera A, Pignataro A, Calissano P, Amadoro G. Latina V, et al. Among authors: sciacca mfm. Acta Neuropathol Commun. 2025 May 29;13(1):121. doi: 10.1186/s40478-025-02022-y. Acta Neuropathol Commun. 2025. PMID: 40442822 Free PMC article.
Folding mechanisms steer the amyloid fibril formation propensity of highly homologous proteins.
Malgieri G, D'Abrosca G, Pirone L, Toto A, Palmieri M, Russo L, Sciacca MFM, Tatè R, Sivo V, Baglivo I, Majewska R, Coletta M, Pedone PV, Isernia C, De Stefano M, Gianni S, Pedone EM, Milardi D, Fattorusso R. Malgieri G, et al. Among authors: sciacca mfm. Chem Sci. 2018 Mar 1;9(13):3290-3298. doi: 10.1039/c8sc00166a. eCollection 2018 Apr 7. Chem Sci. 2018. PMID: 29780459 Free PMC article.
39 results