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Page 1
Gut microbiota modulation through Akkermansia spp. supplementation increases CAR-T cell potency.
Marcos-Kovandzic L, Avagliano M, Ben Khelil M, Srikanthan J, Abdallah R, Petrocelli V, Rengassamy J, Alfaro A, Bied M, Fidelle M, Ferrere G, Daillere R, Arbab A, Amine-Hneineh R, Pages A, Dartigues P, Ly P, Simon S, Durand S, Gottschlich A, Ginhoux F, Bleriot C, Liu P, Zhao L, Creusot L, Rolhion N, Kroemer G, Menger L, Kobold S, Castilla-Llorente C, Sokol H, Casola S, Pasolli E, Zitvogel L, Bigenwald C. Marcos-Kovandzic L, et al. Among authors: kobold s. Cancer Discov. 2025 Jun 11. doi: 10.1158/2159-8290.CD-24-1230. Online ahead of print. Cancer Discov. 2025. PMID: 40498998
A novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice.
Wiedemann GM, Jacobi SJ, Chaloupka M, Krächan A, Hamm S, Strobl S, Baumgartner R, Rothenfusser S, Duewell P, Endres S, Kobold S. Wiedemann GM, et al. Among authors: kobold s. Oncoimmunology. 2016 May 31;5(7):e1189051. doi: 10.1080/2162402X.2016.1189051. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622045 Free PMC article.
C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer.
Rapp M, Grassmann S, Chaloupka M, Layritz P, Kruger S, Ormanns S, Rataj F, Janssen KP, Endres S, Anz D, Kobold S. Rapp M, et al. Among authors: kobold s. Oncoimmunology. 2015 Oct 29;5(3):e1105428. doi: 10.1080/2162402X.2015.1105428. eCollection 2016 Mar. Oncoimmunology. 2015. PMID: 27195186 Free PMC article.
Antibody-mediated inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity.
Ferrari de Andrade L, Tay RE, Pan D, Luoma AM, Ito Y, Badrinath S, Tsoucas D, Franz B, May KF Jr, Harvey CJ, Kobold S, Pyrdol JW, Yoon C, Yuan GC, Hodi FS, Dranoff G, Wucherpfennig KW. Ferrari de Andrade L, et al. Among authors: kobold s. Science. 2018 Mar 30;359(6383):1537-1542. doi: 10.1126/science.aao0505. Science. 2018. PMID: 29599246 Free PMC article.
Prolonged time to treatment initiation in advanced pancreatic cancer patients has no major effect on treatment outcome: a retrospective cohort study controlled for lead time bias and waiting time paradox.
Kruger S, Schirle K, Haas M, Crispin A, Schirra J, Mayerle J, D'Haese JG, Kunz WG, Ricke J, Ormanns S, Kirchner T, Kobold S, Ilmer M, Gebauer L, Westphalen CB, von Bergwelt-Baildon M, Werner J, Heinemann V, Boeck S. Kruger S, et al. Among authors: kobold s. J Cancer Res Clin Oncol. 2020 Feb;146(2):391-399. doi: 10.1007/s00432-019-03061-4. Epub 2019 Oct 23. J Cancer Res Clin Oncol. 2020. PMID: 31642961
TetraMabs: simultaneous targeting of four oncogenic receptor tyrosine kinases for tumor growth inhibition in heterogeneous tumor cell populations.
Castoldi R, Schanzer J, Panke C, Jucknischke U, Neubert NJ, Croasdale R, Scheuer W, Auer J, Klein C, Niederfellner G, Kobold S, Sustmann C. Castoldi R, et al. Among authors: kobold s. Protein Eng Des Sel. 2016 Oct;29(10):467-475. doi: 10.1093/protein/gzw037. Epub 2016 Aug 29. Protein Eng Des Sel. 2016. PMID: 27578890 Free PMC article.
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies.
Dickopf S, Buldun C, Vasic V, Georges G, Hage C, Mayer K, Forster M, Wessels U, Stubenrauch KG, Benz J, Ehler A, Lauer ME, Ringler P, Kobold S, Endres S, Klein C, Brinkmann U. Dickopf S, et al. Among authors: kobold s. Biol Chem. 2022 Jan 20;403(5-6):495-508. doi: 10.1515/hsz-2021-0401. Print 2022 Apr 26. Biol Chem. 2022. PMID: 35073465 Free PMC article.
169 results