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Page 1
Gut microbiota modulation through Akkermansia spp. supplementation increases CAR-T cell potency.
Marcos-Kovandzic L, Avagliano M, Ben Khelil M, Srikanthan J, Abdallah R, Petrocelli V, Rengassamy J, Alfaro A, Bied M, Fidelle M, Ferrere G, Daillere R, Arbab A, Amine-Hneineh R, Pages A, Dartigues P, Ly P, Simon S, Durand S, Gottschlich A, Ginhoux F, Bleriot C, Liu P, Zhao L, Creusot L, Rolhion N, Kroemer G, Menger L, Kobold S, Castilla-Llorente C, Sokol H, Casola S, Pasolli E, Zitvogel L, Bigenwald C. Marcos-Kovandzic L, et al. Among authors: menger l. Cancer Discov. 2025 Jun 11. doi: 10.1158/2159-8290.CD-24-1230. Online ahead of print. Cancer Discov. 2025. PMID: 40498998
Ablation of FAS confers allogeneic CD3- CAR T cells with resistance to rejection by T cells and natural killer cells.
Menegatti S, Lopez-Cobo S, Sutra Del Galy A, Fuentealba J, Silva L, Perrin L, Heurtebise-Chrétien S, Pottez-Jouatte V, Darbois A, Burgdorf N, Privat AL, Simon A, Laprie-Sentenac M, Saitakis M, Wick B, Webber BR, Moriarity BS, Lantz O, Amigorena S, Menger L. Menegatti S, et al. Among authors: menger l. Nat Biomed Eng. 2024 Dec;8(12):1651-1664. doi: 10.1038/s41551-024-01282-8. Epub 2024 Nov 18. Nat Biomed Eng. 2024. PMID: 39558141
Tumor-intrinsic sensitivity to the pro-apoptotic effects of IFN-γ is a major determinant of CD4+ CAR T-cell antitumor activity.
Boulch M, Cazaux M, Cuffel A, Guerin MV, Garcia Z, Alonso R, Lemaître F, Beer A, Corre B, Menger L, Grandjean CL, Morin F, Thieblemont C, Caillat-Zucman S, Bousso P. Boulch M, et al. Among authors: menger l. Nat Cancer. 2023 Jul;4(7):968-983. doi: 10.1038/s43018-023-00570-7. Epub 2023 May 29. Nat Cancer. 2023. PMID: 37248395 Free PMC article.
Acute Influenza Infection Promotes Lung Tumor Growth by Reprogramming the Tumor Microenvironment.
Garmendia I, Varthaman A, Marmier S, Angrini M, Matchoua I, Darbois-Delahousse A, Josseaume N, Foy PE, Roumenina LT, Naouar N, Meylan M, Sibéril S, Russick J, Joubert PE, Leroy K, Damotte D, Mansuet-Lupo A, Wislez M, Alifano M, Menger L, Garcia-Verdugo I, Sallenave JM, Lantz O, Petitprez F, Cremer I. Garmendia I, et al. Among authors: menger l. Cancer Immunol Res. 2023 Apr 3;11(4):530-545. doi: 10.1158/2326-6066.CIR-22-0534. Cancer Immunol Res. 2023. PMID: 36883368
Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma.
Costa A, Thirant C, Kramdi A, Pierre-Eugène C, Louis-Brennetot C, Blanchard O, Surdez D, Gruel N, Lapouble E, Pierron G, Sitbon D, Brisse H, Gauthier A, Fréneaux P, Bohec M, Raynal V, Baulande S, Leclere R, Champenois G, Nicolas A, Meseure D, Bellini A, Marabelle A, Geoerger B, Mechta-Grigoriou F, Schleiermacher G, Menger L, Delattre O, Janoueix-Lerosey I. Costa A, et al. Among authors: menger l. J Immunother Cancer. 2022 Aug;10(8):e004807. doi: 10.1136/jitc-2022-004807. J Immunother Cancer. 2022. PMID: 36054452 Free PMC article.
Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer.
Nalio Ramos R, Missolo-Koussou Y, Gerber-Ferder Y, Bromley CP, Bugatti M, Núñez NG, Tosello Boari J, Richer W, Menger L, Denizeau J, Sedlik C, Caudana P, Kotsias F, Niborski LL, Viel S, Bohec M, Lameiras S, Baulande S, Lesage L, Nicolas A, Meseure D, Vincent-Salomon A, Reyal F, Dutertre CA, Ginhoux F, Vimeux L, Donnadieu E, Buttard B, Galon J, Zelenay S, Vermi W, Guermonprez P, Piaggio E, Helft J. Nalio Ramos R, et al. Among authors: menger l. Cell. 2022 Mar 31;185(7):1189-1207.e25. doi: 10.1016/j.cell.2022.02.021. Epub 2022 Mar 23. Cell. 2022. PMID: 35325594 Free article.
Methods to edit T cells for cancer immunotherapy.
Lucibello F, Menegatti S, Menger L. Lucibello F, et al. Among authors: menger l. Methods Enzymol. 2020;631:107-135. doi: 10.1016/bs.mie.2019.05.048. Epub 2019 Jul 25. Methods Enzymol. 2020. PMID: 31948544 Review.
35 results