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Senescence-resistant human mesenchymal progenitor cells counter aging in primates.
Lei J, Xin Z, Liu N, Ning T, Jing Y, Qiao Y, He Z, Jiang M, Yang Y, Zhang Z, Zhao L, Li J, Lv D, Yan Y, Zhang H, Xiao L, Zhang B, Huang H, Sun S, Zheng F, Jiang X, Lu H, Dong X, Yue S, Ma C, Shuai J, Ji Z, Liu F, Ye Y, Yan K, Hu Q, Xu G, Zhao Q, Wu R, Cai Y, Fan Y, Jing Y, Wang Q, Reddy P, Lu X, Zheng Z, Liu B, Haghani A, Ma S, Suzuki K, Rodriguez Esteban C, Yang J, Song M, Horvath S, Zhang W, Li W, Xiang AP, Zhu L, Fu X, Zhao G, Belmonte JCI, Qu J, Wang S, Liu GH. Lei J, et al. Among authors: song m. Cell. 2025 Jun 13:S0092-8674(25)00571-9. doi: 10.1016/j.cell.2025.05.021. Online ahead of print. Cell. 2025. PMID: 40516525
Resurrection of endogenous retroviruses during aging reinforces senescence.
Liu X, Liu Z, Wu Z, Ren J, Fan Y, Sun L, Cao G, Niu Y, Zhang B, Ji Q, Jiang X, Wang C, Wang Q, Ji Z, Li L, Esteban CR, Yan K, Li W, Cai Y, Wang S, Zheng A, Zhang YE, Tan S, Cai Y, Song M, Lu F, Tang F, Ji W, Zhou Q, Belmonte JCI, Zhang W, Qu J, Liu GH. Liu X, et al. Among authors: song m. Cell. 2023 Jan 19;186(2):287-304.e26. doi: 10.1016/j.cell.2022.12.017. Epub 2023 Jan 6. Cell. 2023. PMID: 36610399 Free article.
Metformin decelerates aging clock in male monkeys.
Yang Y, Lu X, Liu N, Ma S, Zhang H, Zhang Z, Yang K, Jiang M, Zheng Z, Qiao Y, Hu Q, Huang Y, Zhang Y, Xiong M, Liu L, Jiang X, Reddy P, Dong X, Xu F, Wang Q, Zhao Q, Lei J, Sun S, Jing Y, Li J, Cai Y, Fan Y, Yan K, Jing Y, Haghani A, Xing M, Zhang X, Zhu G, Song W, Horvath S, Rodriguez Esteban C, Song M, Wang S, Zhao G, Li W, Izpisua Belmonte JC, Qu J, Zhang W, Liu GH. Yang Y, et al. Among authors: song w, song m. Cell. 2024 Oct 31;187(22):6358-6378.e29. doi: 10.1016/j.cell.2024.08.021. Epub 2024 Sep 12. Cell. 2024. PMID: 39270656
Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging.
Ma S, Ji Z, Zhang B, Geng L, Cai Y, Nie C, Li J, Zuo Y, Sun Y, Xu G, Liu B, Ai J, Liu F, Zhao L, Zhang J, Zhang H, Sun S, Huang H, Zhang Y, Ye Y, Fan Y, Zheng F, Hu J, Zhang B, Li J, Feng X, Zhang F, Zhuang Y, Li T, Yu Y, Bao Z, Pan S, Rodriguez Esteban C, Liu Z, Deng H, Wen F, Song M, Wang S, Zhu G, Yang J, Jiang T, Song W, Izpisua Belmonte JC, Qu J, Zhang W, Gu Y, Liu GH. Ma S, et al. Among authors: song w, song m. Cell. 2024 Nov 27;187(24):7025-7044.e34. doi: 10.1016/j.cell.2024.10.019. Epub 2024 Nov 4. Cell. 2024. PMID: 39500323
Destabilizing heterochromatin by APOE mediates senescence.
Zhao H, Ji Q, Wu Z, Wang S, Ren J, Yan K, Wang Z, Hu J, Chu Q, Hu H, Cai Y, Wang Q, Huang D, Ji Z, Li J, Belmonte JCI, Song M, Zhang W, Qu J, Liu GH. Zhao H, et al. Among authors: song m. Nat Aging. 2022 Apr;2(4):303-316. doi: 10.1038/s43587-022-00186-z. Epub 2022 Mar 28. Nat Aging. 2022. PMID: 37117743
Author Correction: A single-cell transcriptomic landscape of primate arterial aging.
Zhang W, Zhang S, Yan P, Ren J, Song M, Li J, Lei J, Pan H, Wang S, Ma X, Ma S, Li H, Sun F, Wan H, Li W, Chan P, Zhou Q, Liu GH, Tang F, Qu J. Zhang W, et al. Among authors: song m. Nat Commun. 2025 Feb 25;16(1):1949. doi: 10.1038/s41467-025-57130-z. Nat Commun. 2025. PMID: 40000689 Free PMC article. No abstract available.
Acting on ethics and governance of aging research.
Peng Y, Ding L, Song M, Xiao Z, Lv J, Liu GH. Peng Y, et al. Among authors: song m. Trends Mol Med. 2023 Jun;29(6):419-421. doi: 10.1016/j.molmed.2023.03.004. Epub 2023 Apr 26. Trends Mol Med. 2023. PMID: 37117070
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