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329 results

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Page 1
Kupffer cell programming by maternal obesity triggers fatty liver disease.
Huang H, Balzer NR, Seep L, Splichalova I, Blank-Stein N, Viola MF, Franco Taveras E, Acil K, Fink D, Petrovic F, Makdissi N, Bayar S, Mauel K, Radwaniak C, Zurkovic J, Kayvanjoo AH, Wunderling K, Jessen M, Yaghmour MH, Kenner L, Ulas T, Grein S, Schultze JL, Scott CL, Guilliams M, Liu Z, Ginhoux F, Beyer MD, Thiele C, Meissner F, Hasenauer J, Wachten D, Mass E. Huang H, et al. Among authors: schultze jl. Nature. 2025 Jun 18. doi: 10.1038/s41586-025-09190-w. Online ahead of print. Nature. 2025. PMID: 40533564
The life-saving benefit of dexamethasone in severe COVID-19 is linked to a reversal of monocyte dysregulation.
Knoll R, Helbig ET, Dahm K, Bolaji O, Hamm F, Dietrich O, van Uelft M, Müller S, Bonaguro L, Schulte-Schrepping J, Petrov L, Krämer B, Kraut M, Stubbemann P, Thibeault C, Brumhard S, Theis H, Hack G, De Domenico E, Nattermann J, Becker M, Beyer MD, Hillus D, Georg P, Loers C, Tiedemann J, Tober-Lau P, Lippert L, Millet Pascual-Leone B, Tacke F, Rohde G, Suttorp N, Witzenrath M; CAPNETZ Study Group; Pa-COVID-19 Study Group; Saliba AE, Ulas T, Polansky JK, Sawitzki B, Sander LE, Schultze JL, Aschenbrenner AC, Kurth F. Knoll R, et al. Among authors: schultze jl. Cell. 2024 Aug 8;187(16):4318-4335.e20. doi: 10.1016/j.cell.2024.06.014. Epub 2024 Jul 3. Cell. 2024. PMID: 38964327 Free article.
Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition.
Suen TK, Al B, Ulas T, Reusch N, Bahrar H, Bekkering S, Bhat J, Kabelitz D, Schultze JL, van de Veerdonk FL, van Lennep JR, Riksen NP, Joosten LAB, Netea MG, Placek K. Suen TK, et al. Among authors: schultze jl. Immunology. 2025 Jul;175(3):300-322. doi: 10.1111/imm.13931. Epub 2025 Apr 22. Immunology. 2025. PMID: 40264329 Free PMC article.
Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression.
Köhne M, Shakiba MH, Schmidleithner L, Schulte-Schrepping J, Scholz R, Elmzzahi T, Sommer D, Li Y, Carraro C, De Domenico E, Wißfeld J, Händler K, Hamada D, Frolov A, Cheng X, Baumgart AK, Holsten L, Osei-Sarpong C, Bourry S, Thabet Y, Renken H, Paulusch S, Sadlon T, Buch T, Wunderlich FT, Wickenhauser C, Alferink J, Kuhlmann T, Geyer M, Bonaguro L, Barry SC, Schultze JL, Beyer MD. Köhne M, et al. Among authors: schultze jl. Cell Rep. 2025 Jun 17;44(7):115866. doi: 10.1016/j.celrep.2025.115866. Online ahead of print. Cell Rep. 2025. PMID: 40531625 Free article.
Immune and metabolic effects of African heritage diets versus Western diets in men: a randomized controlled trial.
Temba GS, Pecht T, Kullaya VI, Vadaq N, Mosha MV, Ulas T, Kanungo S, van Emst L, Bonaguro L, Schulte-Schrepping J, Mafuru E, Lionetti P, Mhlanga MM, van der Ven AJ, Cavalieri D, Joosten LAB, Kavishe RA, Mmbaga BT, Schultze JL, Netea MG, de Mast Q. Temba GS, et al. Among authors: schultze jl. Nat Med. 2025 May;31(5):1698-1711. doi: 10.1038/s41591-025-03602-0. Epub 2025 Apr 3. Nat Med. 2025. PMID: 40181181 Free PMC article. Clinical Trial.
Oxidative phosphorylation is a key feature of neonatal monocyte immunometabolism promoting myeloid differentiation after birth.
Ehlers G, Tödtmann AM, Holsten L, Willers M, Heckmann J, Schöning J, Richter M, Heinemann AS, Pirr S, Heinz A, Dopfer C, Händler K, Becker M, Büchel J, Wöckel A, von Kaisenberg C, Hansen G, Hiller K, Schultze JL, Härtel C, Kastenmüller W, Vaeth M, Ulas T, Viemann D. Ehlers G, et al. Among authors: schultze jl. Nat Commun. 2025 Mar 6;16(1):2239. doi: 10.1038/s41467-025-57357-w. Nat Commun. 2025. PMID: 40050264 Free PMC article.
329 results