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Page 1
Olorofim for the treatment of invasive fungal diseases in patients with few or no therapeutic options: a single-arm, open-label, phase 2b study.
Maertens JA, Thompson GR 3rd, Spec A, Donovan FM, Hammond SP, Bruns AHW, Rahav G, Shoham S, Johnson R, Rijnders B, Schaenman J, Hoenigl M, Morrissey CO, Mehta SR, Heath CH, Koehler P, Paterson DL, Slavin MA, Fortún J, Nguyen MH, Patterson TF, Uspenskaya O, Van de Veerdonk FL, Verweij PE, Aoun M, Georgala A, Alexander BD, Chayakulkeeree M, Mehra V, Miceli MH, Sikka MK, Solé A, Walsh TJ, Aguado JM, Holland SM, Moussa M, Rautemaa-Richardson R, Bazaz R, Schwartz S, Walsh SR, Plate M, Yehudai-Ofir D, Brüggemann RJ, Cornely OA, Ostrosky-Zeichner L, Vazquez JA, White PL, Cornelissen K, Ross GG, Fitton L, Dane A, Zinzi D, Rex JH, Chen SC. Maertens JA, et al. Among authors: spec a. Lancet Infect Dis. 2025 Jun 17:S1473-3099(25)00224-5. doi: 10.1016/S1473-3099(25)00224-5. Online ahead of print. Lancet Infect Dis. 2025. PMID: 40541222
Coronavirus Disease 2019-Associated Invasive Fungal Infection.
Baddley JW, Thompson GR 3rd, Chen SC, White PL, Johnson MD, Nguyen MH, Schwartz IS, Spec A, Ostrosky-Zeichner L, Jackson BR, Patterson TF, Pappas PG. Baddley JW, et al. Among authors: spec a. Open Forum Infect Dis. 2021 Nov 16;8(12):ofab510. doi: 10.1093/ofid/ofab510. eCollection 2021 Dec. Open Forum Infect Dis. 2021. PMID: 34877364 Free PMC article.
Noninvasive Testing and Surrogate Markers in Invasive Fungal Diseases.
Thompson GR 3rd, Boulware DR, Bahr NC, Clancy CJ, Harrison TS, Kauffman CA, Le T, Miceli MH, Mylonakis E, Nguyen MH, Ostrosky-Zeichner L, Patterson TF, Perfect JR, Spec A, Kontoyiannis DP, Pappas PG. Thompson GR 3rd, et al. Among authors: spec a. Open Forum Infect Dis. 2022 Mar 4;9(6):ofac112. doi: 10.1093/ofid/ofac112. eCollection 2022 Jun. Open Forum Infect Dis. 2022. PMID: 35611348 Free PMC article.
Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.
Cornely OA, Sprute R, Bassetti M, Chen SC, Groll AH, Kurzai O, Lass-Flörl C, Ostrosky-Zeichner L, Rautemaa-Richardson R, Revathi G, Santolaya ME, White PL, Alastruey-Izquierdo A, Arendrup MC, Baddley J, Barac A, Ben-Ami R, Brink AJ, Grothe JH, Guinea J, Hagen F, Hochhegger B, Hoenigl M, Husain S, Jabeen K, Jensen HE, Kanj SS, Koehler P, Lehrnbecher T, Lewis RE, Meis JF, Nguyen MH, Pana ZD, Rath PM, Reinhold I, Seidel D, Takazono T, Vinh DC, Zhang SX, Afeltra J, Al-Hatmi AMS, Arastehfar A, Arikan-Akdagli S, Bongomin F, Carlesse F, Chayakulkeeree M, Chai LYA, Chamani-Tabriz L, Chiller T, Chowdhary A, Clancy CJ, Colombo AL, Cortegiani A, Corzo Leon DE, Drgona L, Dudakova A, Farooqi J, Gago S, Ilkit M, Jenks JD, Klimko N, Krause R, Kumar A, Lagrou K, Lionakis MS, Lmimouni BE, Mansour MK, Meletiadis J, Mellinghoff SC, Mer M, Mikulska M, Montravers P, Neoh CF, Ozenci V, Pagano L, Pappas P, Patterson TF, Puerta-Alcalde P, Rahimli L, Rahn S, Roilides E, Rotstein C, Ruegamer T, Sabino R, Salmanton-García J, Schwartz IS, Segal E, Sidharthan N, Singhal T, Sinko J, Soman R, Spec A, Steinmann J, Stemler J, Taj-Aldeen SJ, Talento AF, Thompson GR 3rd, Toebben C, Villanueva-Lozano H, Wahyu… See abstract for full author list ➔ Cornely OA, et al. Among authors: spec a. Lancet Infect Dis. 2025 May;25(5):e280-e293. doi: 10.1016/S1473-3099(24)00749-7. Epub 2025 Feb 13. Lancet Infect Dis. 2025. PMID: 39956121 Free article. Review.
Global guideline for the diagnosis and management of the endemic mycoses: an initiative of the European Confederation of Medical Mycology in cooperation with the International Society for Human and Animal Mycology.
Thompson GR 3rd, Le T, Chindamporn A, Kauffman CA, Alastruey-Izquierdo A, Ampel NM, Andes DR, Armstrong-James D, Ayanlowo O, Baddley JW, Barker BM, Lopes Bezerra L, Buitrago MJ, Chamani-Tabriz L, Chan JFW, Chayakulkeeree M, Cornely OA, Cunwei C, Gangneux JP, Govender NP, Hagen F, Hedayati MT, Hohl TM, Jouvion G, Kenyon C, Kibbler CC, Klimko N, Kong DCM, Krause R, Lee Lee L, Meintjes G, Miceli MH, Rath PM, Spec A, Queiroz-Telles F, Variava E, Verweij PE, Schwartz IS, Pasqualotto AC. Thompson GR 3rd, et al. Among authors: spec a. Lancet Infect Dis. 2021 Dec;21(12):e364-e374. doi: 10.1016/S1473-3099(21)00191-2. Epub 2021 Aug 6. Lancet Infect Dis. 2021. PMID: 34364529 Free PMC article. Review.
Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM.
Chang CC, Harrison TS, Bicanic TA, Chayakulkeeree M, Sorrell TC, Warris A, Hagen F, Spec A, Oladele R, Govender NP, Chen SC, Mody CH, Groll AH, Chen YC, Lionakis MS, Alanio A, Castañeda E, Lizarazo J, Vidal JE, Takazono T, Hoenigl M, Alffenaar JW, Gangneux JP, Soman R, Zhu LP, Bonifaz A, Jarvis JN, Day JN, Klimko N, Salmanton-García J, Jouvion G, Meya DB, Lawrence D, Rahn S, Bongomin F, McMullan BJ, Sprute R, Nyazika TK, Beardsley J, Carlesse F, Heath CH, Ayanlowo OO, Mashedi OM, Queiroz-Telles Filho F, Hosseinipour MC, Patel AK, Temfack E, Singh N, Cornely OA, Boulware DR, Lortholary O, Pappas PG, Perfect JR. Chang CC, et al. Among authors: spec a. Lancet Infect Dis. 2024 Aug;24(8):e495-e512. doi: 10.1016/S1473-3099(23)00731-4. Epub 2024 Feb 9. Lancet Infect Dis. 2024. PMID: 38346436 Review.
MSG-15: Super-Bioavailability Itraconazole Versus Conventional Itraconazole in the Treatment of Endemic Mycoses-A Multicenter, Open-Label, Randomized Comparative Trial.
Spec A, Thompson GR, Miceli MH, Hayes J, Proia L, McKinsey D, Arauz AB, Mullane K, Young JA, McGwin G, McMullen R, Plumley T, Moore MK, McDowell LA, Jones C, Pappas PG. Spec A, et al. Open Forum Infect Dis. 2024 Jan 29;11(3):ofae010. doi: 10.1093/ofid/ofae010. eCollection 2024 Mar. Open Forum Infect Dis. 2024. PMID: 38440302 Free PMC article.
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