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The ability of SAMHD1-deficient monocytes to trigger the type I IFN response depends on cGAS and mitochondrial DNA.
Rabinowitz J, Vila IK, Luchsinger C, Bertelli C, Schüssler M, Taffoni C, Cui B, Dai AZ, Rashid MM, Cisneros WJ, Cornish D, Redondo J, Jackson-Jones KA, Simons LM, Lorenzo-Redondo R, Laguette N, Hultquist JF, Diaz-Griffero F. Rabinowitz J, et al. Among authors: cui b. J Biol Chem. 2025 Jun 26:110430. doi: 10.1016/j.jbc.2025.110430. Online ahead of print. J Biol Chem. 2025. PMID: 40581121
Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages.
Liu SS, Lv XX, Liu C, Qi J, Li YX, Wei XP, Li K, Hua F, Cui B, Zhang XW, Yu JJ, Yu JM, Wang F, Shang S, Zhao CX, Hou XY, Yao ZG, Li PP, Li X, Huang B, Hu ZW. Liu SS, et al. Among authors: cui b. Immunity. 2025 Jun 24:S1074-7613(25)00284-5. doi: 10.1016/j.immuni.2025.06.015. Online ahead of print. Immunity. 2025. PMID: 40562039 No abstract available.
3,041 results