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NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β-TrCP1/FBXO5 Axis.
Tong Y, Lear TB, Tuncer F, Villandre JJ, Boudreau ÁN, Lin B, Alfaras I, Kennerdell JR, Camarco DP, Larsen MB, Hua Y, Chen Y, Chandler ME, Pineda R, Barratt-Boyes SM, Evankovich JW, Finkel T, Liu Y, Chen BB. Tong Y, et al. Among authors: villandre jj. Adv Sci (Weinh). 2025 Jun 27:e00798. doi: 10.1002/advs.202500798. Online ahead of print. Adv Sci (Weinh). 2025. PMID: 40577599
Inhibition of virally induced TFEB proteasomal degradation as a host-centric therapeutic approach for coronaviral infection.
Lear TB, Larsen MB, Lin B, Treat BR, Cao Q, Boudreau ÁN, Lockwood KC, Alfaras I, Kennerdell JR, Salminen L, Camarco DP, Tong Y, Ma J, Liu J, Tan JX, Tuncer F, Villandre JJ, Hertzel L, Myerburg MM, Chen Y, St Croix C, Sekine Y, Evankovich JW, Barratt-Boyes SM, Finkel T, Chen BB, Liu Y. Lear TB, et al. Among authors: villandre jj. Sci Adv. 2025 Jun 6;11(23):eadv4033. doi: 10.1126/sciadv.adv4033. Epub 2025 Jun 4. Sci Adv. 2025. PMID: 40465712 Free PMC article.
Plasma 1,3-β-d-glucan levels predict adverse clinical outcomes in critical illness.
Kitsios GD, Kotok D, Yang H, Finkelman MA, Zhang Y, Britton N, Li X, Levochkina MS, Wagner AK, Schaefer C, Villandre JJ, Guo R, Evankovich JW, Bain W, Shah F, Zhang Y, Methé BA, Benos PV, McVerry BJ, Morris A. Kitsios GD, et al. Among authors: villandre jj. JCI Insight. 2021 Jul 22;6(14):e141277. doi: 10.1172/jci.insight.141277. JCI Insight. 2021. PMID: 34128840 Free PMC article.