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Clinical benefit and cost of plasma-first next-generation sequencing in patients with newly diagnosed advanced non-small cell lung cancer in Ireland: The PLAN study.
O'Reilly D, O'Grady A, Hayes C, Piggott L, Keane R, Fitzpatrick OM, Conroy M, Aretz NK, Synnott D, Dillon R, Dowling GP, Ryan DJ, O'Brien E, Morgan R, Breathnach O, Grogan L, Morris P, Greally M, Teo MY, Murphy A, Ryan G, Counihan I, Ryan C, Barrett H, O'Shea AM, Cuffe S, Korpanty G, Prior L, Barr MP, Finn S, O'Brien C, McCarron S, Cummins R, Toomey S, Dowling CM, Glavey S, Hennessy BT, Sorensen J, Bennett K, Nadarajan P, Doyle B, Naidoo J. O'Reilly D, et al. Among authors: o grady a. Eur J Cancer. 2025 Jun 17;225:115582. doi: 10.1016/j.ejca.2025.115582. Online ahead of print. Eur J Cancer. 2025. PMID: 40578048
Neuronal α-Synuclein Disease Stage Progression over 5 Years.
Simuni T, Gochanour C, Nair AR, Brumm MC, Coffey C, Poston KL, Chahine LM, Weintraub D, Tanner CM, Gonzalez-Latapi P, Kopil CM, Xiao Y, Chowdhury S, Dam T, Pagano G, Stephenson D, Siderowf A, Dunn B, Marek K; NSD Working Group the Parkinson's Progression Markers Initiative. Simuni T, et al. Mov Disord. 2025 Apr 30. doi: 10.1002/mds.30191. Online ahead of print. Mov Disord. 2025. PMID: 40302527
The LRRK2 p.L1795F variant causes Parkinson's disease in the European population.
Lange LM, Levine K, Fox SH, Marras C, Ahmed N, Kuznetsov N, Vitale D, Iwaki H, Lohmann K, Marsili L, Espay AJ, Bauer P, Beetz C, Martin J, Factor SA, Higginbotham LA, Chen H, Leonard H, Nalls MA, Mencacci NE, Morris HR, Singleton AB, Klein C, Blauwendraat C, Fang ZH; Global Parkinson’s Genetics Program (GP2). Lange LM, et al. NPJ Parkinsons Dis. 2025 Mar 25;11(1):58. doi: 10.1038/s41531-025-00896-2. NPJ Parkinsons Dis. 2025. PMID: 40133296 Free PMC article.
LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization.
Chahine LM, Lafontant DE, Choi SH, Iwaki H, Blauwendraat C, Singleton AB, Brumm MC, Alcalay RN, Merchant K, Nudelman KNH, Dagher A, Vo A, Tao Q, Venuto CS, Kieburtz K, Poston KL, Bressman S, Gonzalez-Latapi P, Avants B, Coffey C, Jennings D, Tolosa E, Siderowf A, Marek K, Simuni T; Parkinson’s Progression Markers Initiative. Chahine LM, et al. Brain Commun. 2025 Mar 6;7(2):fcaf103. doi: 10.1093/braincomms/fcaf103. eCollection 2025. Brain Commun. 2025. PMID: 40114783 Free PMC article.
Integrated multiplex analysis of cell death regulators in stage II colorectal cancer suggests patients with 'persister' cell profiles fail to benefit from adjuvant chemotherapy.
Cho S, McDonough E, Graf J, Shia J, Firat C, Urganci N, Surrette C, Lindner A, Salvucci M, Matveeva A, Kisakol B, O'Grady A, Azimi M, Burke JP, McNamara DA, McDade S, Longley DB, Prehn JH, Ginty F. Cho S, et al. Among authors: o grady a. BMJ Oncol. 2024 Aug 6;3(1):e000362. doi: 10.1136/bmjonc-2024-000362. eCollection 2024. BMJ Oncol. 2024. PMID: 39886119 Free PMC article.
189 results