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102 results

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Virtual Cell Challenge: Toward a Turing test for the virtual cell.
Roohani YH, Hua TJ, Tung PY, Bounds LR, Yu FB, Dobin A, Teyssier N, Adduri A, Woodrow A, Plosky BS, Mehta R, Hsu B, Sullivan J, Ricci-Tam C, Li N, Kazaks J, Gilbert LA, Konermann S, Hsu PD, Goodarzi H, Burke DP. Roohani YH, et al. Among authors: gilbert la. Cell. 2025 Jun 26;188(13):3370-3374. doi: 10.1016/j.cell.2025.06.008. Cell. 2025. PMID: 40578317
Genome-wide CRISPR screens identify PTGES3 as a novel AR modulator.
Li H, Melnyk JE, Fu BXH, Shrestha R, Zhang M, Sjöström M, Feng S, Anderson JA, Han W, Chesner LN, Shin HJ, Farsh T, Suarez HJ, Nath S, Chou J, Das R, Egusa EA, Zhu J, Winters A, Maheshwari A, Hua JT, Alshalalfa M, Chen WS, Calvert M, Davicioni E, Kishishita A, Barpanda A, Liu T, Wiita AP, Stohr BA, Siddiqui J, Huang B, Small EJ, Shokat KM, Nelson P, Quigley DA, Wasmuth EV, Gilbert LA, Feng FY. Li H, et al. Among authors: gilbert la. bioRxiv [Preprint]. 2025 May 31:2025.05.29.656244. doi: 10.1101/2025.05.29.656244. bioRxiv. 2025. PMID: 40501535 Free PMC article. Preprint.
EcDNA-borne PVT1 fusion stabilizes oncogenic mRNAs.
Yi H, Zhang S, Swinderman J, Wang Y, Kanakaveti V, Hung KL, Wong IT, Srinivasan S, Curtis EJ, Bhargava-Shah A, Li R, Jones MG, Luebeck J, Zhao Y, Belk JA, Kraft K, Shi Q, Yan X, Pritchard SK, Liang FM, Felsher DW, Gilbert LA, Bafna V, Mischel PS, Chang HY. Yi H, et al. Among authors: gilbert la. bioRxiv [Preprint]. 2025 Apr 3:2025.04.01.646515. doi: 10.1101/2025.04.01.646515. bioRxiv. 2025. PMID: 40236070 Free PMC article. Preprint.
Neddylation as a target in PIK3CA-mutated head and neck cancer.
Naara S, Cui Z, Izgutdina A, VanLandingham NK, Nazarenko A, Woerner LC, Hua Fu BX, Gilbert LA, Johnson DE, Grandis JR. Naara S, et al. Among authors: gilbert la. Biochem Biophys Res Commun. 2025 May 20;759:151703. doi: 10.1016/j.bbrc.2025.151703. Epub 2025 Mar 25. Biochem Biophys Res Commun. 2025. PMID: 40154000 Free PMC article.
Multiplexed epigenetic memory editing using CRISPRoff sensitizes glioblastoma to chemotherapy.
Lin K, Zou C, Hubbard A, Sengelmann S, Goudy L, Wang IC, Sharma R, Pak J, Foster K, Ozawa T, de Groot JF, Phillips J, Vasudevan HN, Raleigh DR, Marson A, Murthy N, Gilbert LA, Berger MS, Liu SJ. Lin K, et al. Among authors: gilbert la. Neuro Oncol. 2025 Feb 25:noaf055. doi: 10.1093/neuonc/noaf055. Online ahead of print. Neuro Oncol. 2025. PMID: 39998382 Free article.
MorPhiC Consortium: towards functional characterization of all human genes.
Adli M, Przybyla L, Burdett T, Burridge PW, Cacheiro P, Chang HY, Engreitz JM, Gilbert LA, Greenleaf WJ, Hsu L, Huangfu D, Hung LH, Kundaje A, Li S, Parkinson H, Qiu X, Robson P, Schürer SC, Shojaie A, Skarnes WC, Smedley D, Studer L, Sun W, Vidović D, Vierbuchen T, White BS, Yeung KY, Yue F, Zhou T; MorPhiC Consortium. Adli M, et al. Among authors: gilbert la. Nature. 2025 Feb;638(8050):351-359. doi: 10.1038/s41586-024-08243-w. Epub 2025 Feb 12. Nature. 2025. PMID: 39939790 Free PMC article.
Androgen Receptor Inhibition Increases MHC Class I Expression and Improves Immune Response in Prostate Cancer.
Chesner LN, Polesso F, Graff JN, Hawley JE, Smith AK, Lundberg A, Das R, Shenoy T, Sjöström M, Zhao F, Hu YM, Linder S, Chen WS, Hawkins RM, Shrestha R, Zhu X, Foye A, Li H, Kim LM, Bhalla M, O'loughlin T, Kuzuoglu-Ozturk D, Hua JT, Badura ML, Wilkinson S, Trostel SY, Bergman AM, Ruggero D, Drake CG, Sowalsky AG, Fong L, Cooperberg MR, Zwart W, Guan X, Ashworth A, Xia Z, Quigley DA, Gilbert LA, Feng FY, Moran AE. Chesner LN, et al. Among authors: gilbert la. Cancer Discov. 2025 Mar 3;15(3):481-494. doi: 10.1158/2159-8290.CD-24-0559. Cancer Discov. 2025. PMID: 39652470 Free PMC article.
102 results