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Metabolic stress and age drive inflammation and cognitive decline in mice and humans.
Elzinga SE, Guo K, Turfah A, Henn RE, Webber-Davis IF, Hayes JM, Pacut CM, Teener SJ, Carter AD, Rigan DM, Allouch AM, Jang DG, Parent R, Glass E, Murphy GG, Lentz SI, Chen KS, Zhao L, Hur J, Feldman EL. Elzinga SE, et al. Among authors: rigan dm. Alzheimers Dement. 2025 Mar;21(3):e70060. doi: 10.1002/alz.70060. Alzheimers Dement. 2025. PMID: 40110679 Free PMC article.
Human neural stem cells restore spatial memory in a transgenic Alzheimer's disease mouse model by an immunomodulating mechanism.
Chen KS, Noureldein MH, McGinley LM, Hayes JM, Rigan DM, Kwentus JF, Mason SN, Mendelson FE, Savelieffd MG, Feldman EL. Chen KS, et al. Among authors: rigan dm. bioRxiv [Preprint]. 2023 Nov 4:2023.11.01.565161. doi: 10.1101/2023.11.01.565161. bioRxiv. 2023. Update in: Front Aging Neurosci. 2023 Dec 14;15:1306004. doi: 10.3389/fnagi.2023.1306004. PMID: 37961246 Free PMC article. Updated. Preprint.