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Profiling antigen-binding affinity of B cell repertoires in tumors by deep learning predicts immune-checkpoint inhibitor treatment outcomes.
Song B, Wang K, Na S, Yao J, Fattah FJ, Martin AL, von Itzstein MS, Yang DM, Liu J, Xue Y, Liang C, Guo Y, Raman I, Zhu C, Dowell JE, Homsi J, Rashdan S, Yang S, Gwin ME, Wu T, Hsiehchen D, Gloria-McCutchen Y, Lu CP, Raj P, Bai XC, Wang J, Conejo-Garcia J, Xie Y, Huang J, Gerber DE, Wang T. Song B, et al. Among authors: rashdan s. Nat Cancer. 2025 Jun 27. doi: 10.1038/s43018-025-01001-5. Online ahead of print. Nat Cancer. 2025. PMID: 40579590
Concerning Safety and Efficacy of Concurrent and Consolidative Durvalumab With Thoracic Radiation Therapy in PDL1-Unselected Stage III Non-Small Cell Lung Cancer: Brief Report.
Zhang Y, Iyengar P, Montalvo S, Westover KD, Rashdan S, Donthireddy K, Kim J, Dowell JE, Drapkin B, Bhalla S, Chukwuma C, Nadeem U, Ahn C, Timmerman RD, Gerber DE. Zhang Y, et al. Among authors: rashdan s. Int J Radiat Oncol Biol Phys. 2025 Jan 1;121(1):68-74. doi: 10.1016/j.ijrobp.2024.07.2333. Epub 2024 Aug 13. Int J Radiat Oncol Biol Phys. 2025. PMID: 39147210 Clinical Trial.
Cmai: Predicting Antigen-Antibody Interactions from Massive Sequencing Data.
Song B, Wang K, Na S, Yao J, Fattah FJ, von Itzstein MS, Yang DM, Liu J, Xue Y, Liang C, Guo Y, Raman I, Zhu C, Dowell JE, Homsi J, Rashdan S, Yang S, Gwin ME, Hsiehchen D, Gloria-McCutchen Y, Raj P, Bai X, Wang J, Conejo-Garcia J, Xie Y, Gerber DE, Huang J, Wang T. Song B, et al. Among authors: rashdan s. bioRxiv [Preprint]. 2024 Jul 12:2024.06.27.601035. doi: 10.1101/2024.06.27.601035. bioRxiv. 2024. PMID: 39005456 Free PMC article. Preprint.
Highly variable timing renders immunotherapy efficacy and toxicity impractical biomarkers of one another in clinical practice.
von Itzstein MS, Yang Y, Wang Y, Hsiehchen D, Sheffield TY, Fattah F, Popat V, Ahmed M, Homsi J, Dowell JE, Rashdan S, Lohrey J, Hammers HJ, Hughes RS, Wang T, Xie Y, Gerber DE. von Itzstein MS, et al. Among authors: rashdan s. Front Immunol. 2024 Apr 16;15:1351739. doi: 10.3389/fimmu.2024.1351739. eCollection 2024. Front Immunol. 2024. PMID: 38690281 Free PMC article.
pan-MHC and cross-Species Prediction of T Cell Receptor-Antigen Binding.
Han Y, Yang Y, Tian Y, Fattah FJ, von Itzstein MS, Hu Y, Zhang M, Kang X, Yang DM, Liu J, Xue Y, Liang C, Raman I, Zhu C, Xiao O, Dowell JE, Homsi J, Rashdan S, Yang S, Gwin ME, Hsiehchen D, Gloria-McCutchen Y, Pan K, Wu F, Gibbons D, Wang X, Yee C, Huang J, Reuben A, Cheng C, Zhang J, Gerber DE, Wang T. Han Y, et al. Among authors: rashdan s. bioRxiv [Preprint]. 2023 Dec 12:2023.12.01.569599. doi: 10.1101/2023.12.01.569599. bioRxiv. 2023. PMID: 38105939 Free PMC article. Preprint.
Systemic immune parameters after prior radiation therapy in patients receiving immune checkpoint inhibitors.
Mundra V, Yang Y, von Itzstein MS, Fattah F, Gonugunta AS, Hannan R, Pop LM, Zhang Y, Wang Y, Sheffield T, Xie Y, Dowell JE, Homsi J, Rashdan S, Park J, Li QZ, Wakeland EK, Gerber DE. Mundra V, et al. Among authors: rashdan s. Transl Oncol. 2023 Aug;34:101689. doi: 10.1016/j.tranon.2023.101689. Epub 2023 Jun 6. Transl Oncol. 2023. PMID: 37285748 Free PMC article.
32 results