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Discovery and Preclinical Profile of ALG-097558, a Pan-Coronavirus 3CLpro Inhibitor.
Bardiot D, McGowan DC, Gupta K, Deval J, Chang S, Jekle A, Liu C, Stevens S, Serebryany V, Tauchert MJ, Maskos K, Stoycheva AD, Ren S, Jaisinghani R, Faucher MO, Lin TI, Boland S, Chaltin P, Marchand A, Wuyts J, De Jonghe S, Jochmans D, Anugu S, Baloju V, Deta K, Welch M, Leyssen P, Neyts J, Laporte M, Abdelnabi R, Hu H, Zhang P, Le K, Chanda S, Smith DB, Raboisson P, Beigelman L, Symons JA, Blatt L, Vandyck K. Bardiot D, et al. Among authors: liu c. J Med Chem. 2025 Jun 30. doi: 10.1021/acs.jmedchem.5c00088. Online ahead of print. J Med Chem. 2025. PMID: 40586480
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