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Mesothelin is a surface antigen present on human meningioma and can be effectively targeted by CAR T-cells.
Ramapriyan R, Barker FG 2nd, Richardson LG, Sun J, Vandecandelaere G, Shim JM, De Vlaminck G, Gaffey M, Grewal EP, Tazhibi M, Morshedy K, Aref AR, Batool SM, Guo X, Ijad N, Balaj L, Wakimoto H, Martinez-Lage M, Frigault MJ, Leick MB, Bernstock JD, Bi WL, Carter BS, Chiocca EA, Dietrich J, Gerstner ER, Boland GM, Nahed BV, Plotkin SR, Jenkins RW, Brastianos PK, Curry WT, Maus MV, Choi BD. Ramapriyan R, et al. Among authors: choi bd. Neuro Oncol. 2025 Jun 28:noaf155. doi: 10.1093/neuonc/noaf155. Online ahead of print. Neuro Oncol. 2025. PMID: 40579924
Secretion of a VEGF-blocking scFv enhances CAR T-cell potency.
Supper VM, Donner H, Birocchi F, Bratt A, Escobar G, Kann MC, Park S, Martin G, Korell F, Takei H, Armstrong A, Parker A, Salas-Benito D, Darnell EP, Bailey SR, Kienka T, Philips M, Bouffard A, Goncalves S, Choi BD, Haradhvala NJ, Maus MV, Leick MB. Supper VM, et al. Among authors: choi bd. Cancer Immunol Res. 2025 Jun 2. doi: 10.1158/2326-6066.CIR-24-0876. Online ahead of print. Cancer Immunol Res. 2025. PMID: 40455064
ROCK-dependent mechanotransduction of macroscale forces drives fibrosis in degenerative spinal disease.
Hadzipasic M, Sten MS, Massaad E, Kiapour A, Connolly ID, Esposito E, Burns R, Nageeb G, Sharif MA, Bradley J, Richardson L, Shaikh S, Choi BD, Nielsen GP, Coumans JC, Borges LF, Shin JH, Grodzinsky AJ, Nia HT, Shankar GM. Hadzipasic M, et al. Among authors: choi bd. Nat Biomed Eng. 2025 May 29. doi: 10.1038/s41551-025-01396-7. Online ahead of print. Nat Biomed Eng. 2025. PMID: 40442480
Gabapentinoids confer survival benefit in human glioblastoma.
Bernstock JD, Mehari M, E Gerstl JV, Meredith DM, Valdes PA, Heesen P, Ambati VS, Krishna S, Chen JA, Arora H, Johnston BR, Negussie M, Grieco K, Nava Gonzales C, Dada A, Lebouille-Veldman AB, Kabir A, Spanehl L, Kaur J, Oten S, Sibih YE, Mekary RA, Daniel A, de Groot JF, Izzy S, Gessler FA, Stone S, Arnaout O, Lu Y, Choi BD, Hall MD, Mehta MP, Odia Y, Friedman GK, Chiocca EA, Peruzzi PP, Smith TR, Hervey-Jumper SL. Bernstock JD, et al. Among authors: choi bd. Nat Commun. 2025 May 15;16(1):4483. doi: 10.1038/s41467-025-59614-4. Nat Commun. 2025. PMID: 40374596 Free PMC article.
Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions.
Khan SM, Wang AZ, Desai RR, McCornack CR, Sun R, Dahiya SM, Foltz JA, Sherpa ND, Leavitt L, West T, Wang AF, Krbanjevic A, Choi BD, Leuthardt EC, Patel B, Charest A, Kim AH, Dunn GP, Petti AA. Khan SM, et al. Among authors: choi bd. bioRxiv [Preprint]. 2025 Apr 22:2025.04.04.647096. doi: 10.1101/2025.04.04.647096. bioRxiv. 2025. PMID: 40235981 Free PMC article. Preprint.
160 results