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204 results

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Mesothelin is a surface antigen present on human meningioma and can be effectively targeted by CAR T-cells.
Ramapriyan R, Barker FG 2nd, Richardson LG, Sun J, Vandecandelaere G, Shim JM, De Vlaminck G, Gaffey M, Grewal EP, Tazhibi M, Morshedy K, Aref AR, Batool SM, Guo X, Ijad N, Balaj L, Wakimoto H, Martinez-Lage M, Frigault MJ, Leick MB, Bernstock JD, Bi WL, Carter BS, Chiocca EA, Dietrich J, Gerstner ER, Boland GM, Nahed BV, Plotkin SR, Jenkins RW, Brastianos PK, Curry WT, Maus MV, Choi BD. Ramapriyan R, et al. Among authors: maus mv. Neuro Oncol. 2025 Jun 28:noaf155. doi: 10.1093/neuonc/noaf155. Online ahead of print. Neuro Oncol. 2025. PMID: 40579924
IFN-γ-resistant CD28 CAR T cells demonstrate increased survival, efficacy, and durability in multiple murine tumor models.
Bailey SR, Takei HN, Escobar G, Kann MC, Bouffard AA, Kienka T, Supper VM, Armstrong A, Salas-Benito D, Phillips MK, Birocchi F, Vatsa S, Silva H, Scarfò I, Wehrli M, Grauwet K, Darnell EP, Graham CE, Leick MB, Korell F, Berger TR, Maus MV. Bailey SR, et al. Among authors: maus mv. Sci Transl Med. 2025 Jun 4;17(801):eadp8166. doi: 10.1126/scitranslmed.adp8166. Epub 2025 Jun 4. Sci Transl Med. 2025. PMID: 40465687
Affinity-matured CD72-targeting Nanobody CAR T-cells Enhance Elimination of Antigen-Low B-cell Malignancies.
Izgutdina A, Rashid T, Temple WC, Patiño-Escobar B, Walunj S, Geng H, Takamatsu H, Gil-Alós D, Kang AS, Ramos E, Chen SY, Johnson H, Nix MA, Naik A, Yuan CM, Wang HW, Aminov S, Sahu S, Larson RC, Carpenter C, Salangsang F, Phojanakong P, Serrano JAC, Tariq I, Zakraoui O, Steri V, Valeri A, Martinez-Lopez J, Maus MV, Parekh S, Verma A, Shah NN, Wiita AP. Izgutdina A, et al. Among authors: maus mv. bioRxiv [Preprint]. 2025 May 15:2025.05.09.653155. doi: 10.1101/2025.05.09.653155. bioRxiv. 2025. PMID: 40463123 Free PMC article. Preprint.
Secretion of a VEGF-blocking scFv enhances CAR T-cell potency.
Supper VM, Donner H, Birocchi F, Bratt A, Escobar G, Kann MC, Park S, Martin G, Korell F, Takei H, Armstrong A, Parker A, Salas-Benito D, Darnell EP, Bailey SR, Kienka T, Philips M, Bouffard A, Goncalves S, Choi BD, Haradhvala NJ, Maus MV, Leick MB. Supper VM, et al. Among authors: maus mv. Cancer Immunol Res. 2025 Jun 2. doi: 10.1158/2326-6066.CIR-24-0876. Online ahead of print. Cancer Immunol Res. 2025. PMID: 40455064
T-ICAHT: Grading and Prognostic Impact of Thrombocytopenia After CAR T-cell Therapy.
Rejeski K, Sanz J, Fei T, Nair MS, Hashmi H, Avigdor A, Beyar-Katz O, Bücklein VL, Curran KJ, Einarsdottir S, Esensten JH, Glaubach N Dr, Golan-Accav N, Gomez-Llobell M, Halamis I, Itzhaki O, Locke FL, Mailankody S, Marcus R, Maus MV, Palomba ML, Park JH, Pasquini MC, Raj SS, Rajeeve S, Salles GA, Scordo M, Shah GL, Shimoni A, Subklewe M, Tix T, Usmani SZ, Valid OB, Valtis YK, Zuckerman T, Shah NN, Perales MA, Shouval R. Rejeski K, et al. Among authors: maus mv. Blood. 2025 Apr 21:blood.2025028833. doi: 10.1182/blood.2025028833. Online ahead of print. Blood. 2025. PMID: 40258181 Free article.
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity.
Jing R, Scarfo I, Najia MA, Lummertz da Rocha E, Han A, Sanborn M, Bingham T, Kubaczka C, Jha DK, Falchetti M, Schlaeger TM, North TE, Maus MV, Daley GQ. Jing R, et al. Among authors: maus mv. Cell Stem Cell. 2025 Apr 3;32(4):670. doi: 10.1016/j.stem.2025.03.006. Epub 2025 Mar 14. Cell Stem Cell. 2025. PMID: 40088890 Free PMC article. No abstract available.
204 results