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Mesothelin is a surface antigen present on human meningioma and can be effectively targeted by CAR T-cells.
Ramapriyan R, Barker FG 2nd, Richardson LG, Sun J, Vandecandelaere G, Shim JM, De Vlaminck G, Gaffey M, Grewal EP, Tazhibi M, Morshedy K, Aref AR, Batool SM, Guo X, Ijad N, Balaj L, Wakimoto H, Martinez-Lage M, Frigault MJ, Leick MB, Bernstock JD, Bi WL, Carter BS, Chiocca EA, Dietrich J, Gerstner ER, Boland GM, Nahed BV, Plotkin SR, Jenkins RW, Brastianos PK, Curry WT, Maus MV, Choi BD. Ramapriyan R, et al. Among authors: morshedy k. Neuro Oncol. 2025 Jun 28:noaf155. doi: 10.1093/neuonc/noaf155. Online ahead of print. Neuro Oncol. 2025. PMID: 40579924