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331 results

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Mesothelin is a surface antigen present on human meningioma and can be effectively targeted by CAR T-cells.
Ramapriyan R, Barker FG 2nd, Richardson LG, Sun J, Vandecandelaere G, Shim JM, De Vlaminck G, Gaffey M, Grewal EP, Tazhibi M, Morshedy K, Aref AR, Batool SM, Guo X, Ijad N, Balaj L, Wakimoto H, Martinez-Lage M, Frigault MJ, Leick MB, Bernstock JD, Bi WL, Carter BS, Chiocca EA, Dietrich J, Gerstner ER, Boland GM, Nahed BV, Plotkin SR, Jenkins RW, Brastianos PK, Curry WT, Maus MV, Choi BD. Ramapriyan R, et al. Among authors: wakimoto h. Neuro Oncol. 2025 Jun 28:noaf155. doi: 10.1093/neuonc/noaf155. Online ahead of print. Neuro Oncol. 2025. PMID: 40579924
Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma.
Hara T, Chanoch-Myers R, Mathewson ND, Myskiw C, Atta L, Bussema L, Eichhorn SW, Greenwald AC, Kinker GS, Rodman C, Gonzalez Castro LN, Wakimoto H, Rozenblatt-Rosen O, Zhuang X, Fan J, Hunter T, Verma IM, Wucherpfennig KW, Regev A, Suvà ML, Tirosh I. Hara T, et al. Among authors: wakimoto h. Cancer Cell. 2025 Jun 9;43(6):1175-1176. doi: 10.1016/j.ccell.2025.05.007. Epub 2025 May 27. Cancer Cell. 2025. PMID: 40436018 No abstract available.
Combination therapy of adagrasib and abemaciclib in non-small cell lung cancer brain metastasis models genomically characterized by KRAS-G12C and homozygous loss of CDKN2A.
Migliarese C, Sadeh Y, Torrini C, Turna Demir F, Nayyar N, Yamazawa E, Ishikawa Y, Ijad N, Summers EJ, Elliott A, Rahbaek L, Saechao B, Hallin J, Brastianos PK, Wakimoto H. Migliarese C, et al. Among authors: wakimoto h. Acta Neuropathol Commun. 2025 May 2;13(1):88. doi: 10.1186/s40478-025-01993-2. Acta Neuropathol Commun. 2025. PMID: 40317086 Free PMC article.
Retraction Note: Target receptor identification and subsequent treatment of resected brain tumors with encapsulated and engineered allogeneic stem cells.
Bhere D, Choi SH, van de Donk P, Hope D, Gortzak K, Kunnummal A, Khalsa J, Lechtich ER, Reinshagen C, Leon V, Nissar N, Bi WL, Feng C, Li H, Zhang YS, Liang SH, Vasdev N, Essayed W, Quevedo PV, Golby A, Banouni N, Palagina A, Abdi R, Fury B, Smirnakis S, Lowe A, Reeve B, Hiller A, Chiocca EA, Prestwich G, Wakimoto H, Bauer G, Shah K. Bhere D, et al. Among authors: wakimoto h. Nat Commun. 2025 Mar 21;16(1):2803. doi: 10.1038/s41467-025-57909-0. Nat Commun. 2025. PMID: 40118851 Free PMC article. No abstract available.
Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
Mayr L, Neyazi S, Schwark K, Trissal M, Beck A, Labelle J, Eder SK, Weiler-Wichtl L, Marques JG, de Biagi-Junior CAO, Lo Cascio C, Chapman O, Sridhar S, Kenkre R, Dutta A, Wang S, Wang J, Hack O, Nascimento A, Nguyen CM, Castellani S, Rozowsky JS, Groves A, Panditharatna E, Cruzeiro GAV, Haase RD, Tabatabai K, Madlener S, Wadden J, Adam T, Kong S, Miclea M, Patel T, Bruckner K, Senfter D, Lämmerer A, Supko J, Guntner AS, Palova H, Neradil J, Stepien N, Lötsch-Gojo D, Berger W, Leiss U, Rosenmayr V, Dorfer C, Dieckmann K, Peyrl A, Azizi AA, Baumgartner A, Slaby O, Pokorna P, Clark LM, Cameron A, Nguyen QD, Wakimoto H, Dubois F, Greenwald NF, Bandopadhayay P, Beroukhim R, Ligon K, Kramm C, Bronsema A, Bailey S, Stucklin AG, Mueller S, Skrypek M, Martinez N, Bowers DC, Jones DTW, Jones C, Jäger N, Sterba J, Müllauer L, Haberler C, Kumar-Sinha C, Chinnaiyan A, Mody R, Chavez L, Furtner J, Koschmann C, Gojo J, Filbin MG. Mayr L, et al. Among authors: wakimoto h. Cancer Cell. 2025 Apr 14;43(4):740-756.e8. doi: 10.1016/j.ccell.2025.02.018. Epub 2025 Mar 13. Cancer Cell. 2025. PMID: 40086436
Immunocompetent murine glioblastoma stem-like cell models exhibiting distinct phenotypes.
Kardani K, Ghouse SM, Din Abdul Jabbar MA, Rajasubramanian N, Sanchez Gil J, Stemmer-Rachamimov A, Soda Y, Martuza RL, Hara T, Wakimoto H, Rabkin SD. Kardani K, et al. Among authors: wakimoto h. Neurooncol Adv. 2024 Dec 7;7(1):vdae215. doi: 10.1093/noajnl/vdae215. eCollection 2025 Jan-Dec. Neurooncol Adv. 2024. PMID: 39896074 Free PMC article.
331 results