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HPV16 neutralizing monoclonal antibodies show evidence for common developmental pathways and public epitopes.
Carter JJ, Hurlburt NK, Scherer EM, Singh S, Rodarte JV, Smith RA, Lewis P, Kinzelman R, Kieltyka J, Cabãn ME, Wipf GC, Pancera M, Galloway DA. Carter JJ, et al. bioRxiv [Preprint]. 2025 Apr 5:2025.03.31.646278. doi: 10.1101/2025.03.31.646278. bioRxiv. 2025. PMID: 40236113 Free PMC article. Preprint.
The other type of mAbs that appeared to be overrepresented were ten mAbs using V (H) 4-34, seven of which also used D (H) 3-16*02 with conserved CDRH3 sequences. Cryo-EM for one of these mAbs, that required the FG-loop for neutralization, was shown to bind one Fab per pent …
The other type of mAbs that appeared to be overrepresented were ten mAbs using V (H) 4-34, seven of which also used D (H) 3-16*02 wit …
21 results