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A TMPRSS6-inhibiting mAb improves disease in a β-thalassemia mouse model and reduces iron in healthy humans.
Lob HE, Singh N, Mohammadi K, Ivanova L, Crowell B, Kim HJ, Kravets L, Das NM, Ray Y, Kim JH, Rottey S, Labriola-Tompkins E, Hassan HE, Farrelly L, Chin HF, Preda M, Spencer Noakes L, Saotome K, Franklin M, Retter MW, Karayusuf E, Flanagan JJ, Olson W, Nannuru KC, Idone V, Burczynski ME, Harari OA, Perlee L, Van Lancker G, Murphy AJ, Economides AN, Hatsell SJ. Lob HE, et al. Among authors: harari oa. JCI Insight. 2025 Jun 23;10(12):e191813. doi: 10.1172/jci.insight.191813. eCollection 2025 Jun 23. JCI Insight. 2025. PMID: 40548380 Free article. Clinical Trial.
Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.
da Rocha JF, Lance ML, Luo R, Schlachter P, Moreira L, Iqbal MA, Kuhn P, Gardner RS, Valaris S, Islam MR, Gassner GM, Mazuera S, Healy K, Shastri S, Hibbert NB, Moran-Figueroa KV, Haley EB, Pfeiffer RD, Aygar S, Kastanenka KV, Brase L, Harari O, Benitez BA, Tucker NR, Wrann CD. da Rocha JF, et al. Among authors: harari o. Nat Neurosci. 2025 Jun 12. doi: 10.1038/s41593-025-01971-w. Online ahead of print. Nat Neurosci. 2025. PMID: 40506544
The choice of viral load endpoint in early phase trials of COVID-19 treatments aiming to reduce 28-day hospitalization and/or death.
Mateja A, Chu E, Murray TA, Bramante CT, Moser C, Givens N, Abdelghany M, Blair C, Chen S, Lat PK, Harari O, Kallewaard NL, Macpherson LF, Boulware DR, Suñer C, Mitjà O, Adam SJ, De Gruttola V, Hughes MD, Rubin D, Smith DM, Potter GE. Mateja A, et al. Among authors: harari o. J Infect Dis. 2025 Jun 3:jiaf282. doi: 10.1093/infdis/jiaf282. Online ahead of print. J Infect Dis. 2025. PMID: 40461945
Use of a national repository of Fourier-transform infrared spectroscopy spectra enables fast detection of silent outbreaks and prevention of spread of new antibiotic-resistant sequence types.
Lurie-Weinberger MN, Temkin E, Kastel O, Bechor M, Bychenko-Banyas D, Efrati-Epchtien R, Levi GD, Rakovitsky N, Keren-Paz A, Carmeli Y; Antimicrobial Resistance Surveillance Group. Lurie-Weinberger MN, et al. Antimicrob Resist Infect Control. 2025 Apr 21;14(1):34. doi: 10.1186/s13756-025-01546-1. Antimicrob Resist Infect Control. 2025. PMID: 40259416 Free PMC article.
Somatic and Stem Cell Bank to Study the Contribution of African Ancestry to Dementia: African iPSC Initiative.
Maina MB, Isah MB, Marsh JA, Muhammad Z, Babazau L, Idris AA, Aladyeva E, Miller N, Starr E, Miller KJ, Lee S, Minaya M, Wray S, Harari O, Goni BW, Serpell LC, Karch CM. Maina MB, et al. Among authors: harari o. medRxiv [Preprint]. 2025 Jan 27:2025.01.24.25320911. doi: 10.1101/2025.01.24.25320911. medRxiv. 2025. Update in: Alzheimers Dement. 2025 Apr;21(4):e70145. doi: 10.1002/alz.70145. PMID: 39974113 Free PMC article. Updated. Preprint.
The patient experience of CHAPLE disease: results from interviews conducted as part of a clinical trial for an ultra-rare condition.
Litcher-Kelly L, Ozen A, Ollis S, Feldman HB, Yaworsky A, Medrano P, Chongsrisawat V, Perlee L, Walker M, Pradeep S, Turner-Bowker DM, Kurolap A, Adiv OE, Lenardo MJ, Harari OA, Jalbert JJ. Litcher-Kelly L, et al. Among authors: harari oa. Orphanet J Rare Dis. 2025 Feb 11;20(1):68. doi: 10.1186/s13023-024-03436-y. Orphanet J Rare Dis. 2025. PMID: 39934837 Free PMC article. Clinical Trial.
Syndication in science: Curated collaboration.
Hurry DB, Izmailova ES, Davies S, Harari O, Stoch SA, Wagner JA. Hurry DB, et al. Among authors: harari o. Clin Transl Sci. 2024 Dec;17(12):e70085. doi: 10.1111/cts.70085. Clin Transl Sci. 2024. PMID: 39614378 Free PMC article. Review.
168 results