Toettcher JE - Search Results

1

A live-cell biosensor of in vivo receptor tyrosine kinase activity reveals feedback regulation of a developmental gradient.

Ho EK, Kim-Yip RP, Simpkins AG, Farahani PE, Oatman HR, Posfai E, Shvartsman SY, Toettcher JE. Ho EK, et al. Among authors: toettcher je. Cell Rep. 2025 Jun 27;44(7):115930. doi: 10.1016/j.celrep.2025.115930. Online ahead of print. Cell Rep. 2025. PMID: 40581929 Free article.

2

Large-scale control over collective cell migration using light-activated epidermal growth factor receptors.

Suh K, Thornton RH, Nguyen L, Farahani PE, Cohen DJ, Toettcher JE. Suh K, et al. Among authors: toettcher je. Cell Syst. 2025 Mar 19;16(3):101203. doi: 10.1016/j.cels.2025.101203. Epub 2025 Mar 3. Cell Syst. 2025. PMID: 40037348

3

In vivo measurements of receptor tyrosine kinase activity reveal feedback regulation of a developmental gradient.

Ho EK, Kim-Yip RP, Simpkins AG, Farahani PE, Oatman HR, Posfai E, Shvartsman SY, Toettcher JE. Ho EK, et al. Among authors: toettcher je. bioRxiv [Preprint]. 2025 Jan 7:2025.01.06.631605. doi: 10.1101/2025.01.06.631605. bioRxiv. 2025. PMID: 39829924 Free PMC article. Preprint.

4

Recording morphogen signals reveals mechanisms underlying gastruloid symmetry breaking.

McNamara HM, Solley SC, Adamson B, Chan MM, Toettcher JE. McNamara HM, et al. Among authors: toettcher je. Nat Cell Biol. 2024 Nov;26(11):1832-1844. doi: 10.1038/s41556-024-01521-9. Epub 2024 Oct 2. Nat Cell Biol. 2024. PMID: 39358450

5

Engineered chimeric receptors for dissecting interferon signaling.

Lin AE, Mesev EV, Toettcher JE, Ploss A. Lin AE, et al. Among authors: toettcher je. J Virol. 2024 Oct 22;98(10):e0168023. doi: 10.1128/jvi.01680-23. Epub 2024 Sep 18. J Virol. 2024. PMID: 39291974 Free PMC article. Review.

6

Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag.

Brumbaugh-Reed EH, Gao Y, Aoki K, Toettcher JE. Brumbaugh-Reed EH, et al. Among authors: toettcher je. Nat Commun. 2024 Aug 7;15(1):6717. doi: 10.1038/s41467-024-50858-0. Nat Commun. 2024. PMID: 39112465 Free PMC article.

7

Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing.

Nguyen LT, Rakestraw NR, Pizzano BLM, Young CB, Huang Y, Beerensson KT, Fang A, Antal SG, Anamisis KV, Peggs CMD, Yan J, Jing Y, Burdine RD, Adamson B, Toettcher JE, Myhrvold C, Jain PK. Nguyen LT, et al. Among authors: toettcher je. bioRxiv [Preprint]. 2024 Jul 10:2024.07.09.602710. doi: 10.1101/2024.07.09.602710. bioRxiv. 2024. PMID: 39026836 Free PMC article. Preprint.

8

Efficient prime editing in two-cell mouse embryos using PEmbryo.

Kim-Yip RP, McNulty R, Joyce B, Mollica A, Chen PJ, Ravisankar P, Law BK, Liu DR, Toettcher JE, Ivakine EA, Posfai E, Adamson B. Kim-Yip RP, et al. Among authors: toettcher je. Nat Biotechnol. 2024 Dec;42(12):1822-1830. doi: 10.1038/s41587-023-02106-x. Epub 2024 Feb 6. Nat Biotechnol. 2024. PMID: 38321114 Free PMC article.

9

Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag.

Brumbaugh-Reed EH, Aoki K, Toettcher JE. Brumbaugh-Reed EH, et al. Among authors: toettcher je. bioRxiv [Preprint]. 2024 Jan 17:2024.01.16.575860. doi: 10.1101/2024.01.16.575860. bioRxiv. 2024. Update in: Nat Commun. 2024 Aug 7;15(1):6717. doi: 10.1038/s41467-024-50858-0. PMID: 38293146 Free PMC article. Updated. Preprint.

10

Membrane-proximal motifs encode differences in signaling strength between type I and III interferon receptors.

Mesev EV, Lin AE, Guare EG, Heller BL, Douam F, Adamson B, Toettcher JE, Ploss A. Mesev EV, et al. Among authors: toettcher je. Sci Signal. 2023 Oct 10;16(806):eadf5494. doi: 10.1126/scisignal.adf5494. Epub 2023 Oct 10. Sci Signal. 2023. PMID: 37816090 Free PMC article.

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