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Page 1
A deep learning and digital archaeology approach for mosquito repellent discovery.
Wei JN, Ruiz C, Vlot M, Sanchez-Lengeling B, Lee BK, Berning L, Vos MW, Henderson RWM, Qian WW, Sanders JN, Ando DM, Groetsch KM, Gerkin RC, Wiltschko AB, Riffell JA, Dechering KJ. Wei JN, et al. Among authors: dechering kj. Chem Senses. 2025 Jul 2:bjaf021. doi: 10.1093/chemse/bjaf021. Online ahead of print. Chem Senses. 2025. PMID: 40598906
Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining.
Godinez-Macias KP, Chen D, Wallis JL, Siegel MG, Adam A, Bopp S, Carolino K, Coulson LB, Durst G, Thathy V, Esherick L, Farringer MA, Flannery EL, Forte B, Liu T, Godoy Magalhaes L, Gupta AK, Istvan ES, Jiang T, Kumpornsin K, Lobb K, McLean KJ, Moura IMR, Okombo J, Payne NC, Plater A, Rao SPS, Siqueira-Neto JL, Somsen BA, Summers RL, Zhang R, Gilson MK, Gamo FJ, Campo B, Baragaña B, Duffy J, Gilbert IH, Lukens AK, Dechering KJ, Niles JC, McNamara CW, Cheng X, Birkholtz LM, Bronkhorst AW, Fidock DA, Wirth DF, Goldberg DE, Lee MCS, Winzeler EA. Godinez-Macias KP, et al. Among authors: dechering kj. NPJ Drug Discov. 2025;2(1):3. doi: 10.1038/s44386-025-00006-5. Epub 2025 Mar 4. NPJ Drug Discov. 2025. PMID: 40066064 Free PMC article.
Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining.
Godinez-Macias KP, Chen D, Wallis JL, Siegel MG, Adam A, Bopp S, Carolino K, Coulson LB, Durst G, Thathy V, Esherick L, Farringer MA, Flannery EL, Forte B, Liu T, Magalhaes LG, Gupta AK, Istvan ES, Jiang T, Kumpornsin K, Lobb K, McLean K, Moura IMR, Okombo J, Payne NC, Plater A, Rao SPS, Siqueira-Neto JL, Somsen BA, Summers RL, Zhang R, Gilson MK, Gamo FJ, Campo B, Baragaña B, Duffy J, Gilbert IH, Lukens AK, Dechering KJ, Niles JC, McNamara CW, Cheng X, Birkholtz LM, Bronkhorst AW, Fidock DA, Wirth DF, Goldberg DE, Lee MCS, Winzeler EA. Godinez-Macias KP, et al. Among authors: dechering kj. Res Sq [Preprint]. 2024 Nov 26:rs.3.rs-5412515. doi: 10.21203/rs.3.rs-5412515/v1. Res Sq. 2024. Update in: NPJ Drug Discov. 2025;2(1):3. doi: 10.1038/s44386-025-00006-5. PMID: 39649165 Free PMC article. Updated. Preprint.
Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission.
Gomez-Gonzalez PJ, Gupta A, Drought LG, Patel A, Okombo J, van der Watt M, Walker-Gray R, Schindler KA, Burkhard AY, Yeo T, Narwal SK, Bloxham TS, Flueck C, Walker EM, Rey JA, Fairhurst KJ, Reader J, Park H, Pollard HG, Stewart LB, Brandner-Garrod L, Kristan M, Sterk GJ, van Nuland YM, Manko E, van Schalkwyk DA, Zheng Y, Leurs R, Dechering KJ, Aguiar ACC, Guido RVC, Pereira DB, Tumwebaze PK, Nosbya SL, Rosenthal PJ, Cooper RA, Palmer M, Parkinson T, Burrows JN, Uhlemann AC, Birkholtz LM, Small-Saunders JL, Duffy J, Fidock DA, Brown A, Gardner M, Baker DA. Gomez-Gonzalez PJ, et al. Among authors: dechering kj. Sci Adv. 2024 Dec 6;10(49):eadq1383. doi: 10.1126/sciadv.adq1383. Epub 2024 Dec 6. Sci Adv. 2024. PMID: 39642214 Free PMC article.
Correction: Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.
Henry NB, Soulama I, Sermé SS, Bolscher JM, Huijs TTG, Coulibaly AS, Sombié S, Ouédraogo N, Diarra A, Zongo S, Guelbéogo WM, Nébié I, Sirima SB, Tiono AB, Pietro A, Collins KA, Dechering KJ, Bousema T. Henry NB, et al. Among authors: dechering kj. PLoS One. 2024 Dec 3;19(12):e0315144. doi: 10.1371/journal.pone.0315144. eCollection 2024. PLoS One. 2024. PMID: 39625922 Free PMC article.
Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.
B Henry N, Soulama I, S Sermé S, Bolscher JM, T G Huijs T, S Coulibaly A, Sombié S, Ouédraogo N, Diarra A, Zongo S, Guelbéogo WM, Nébié I, Sirima SB, Tiono AB, Pietro A, Collins KA, Dechering KJ, Bousema T. B Henry N, et al. Among authors: dechering kj. PLoS One. 2023 Jul 26;18(7):e0284751. doi: 10.1371/journal.pone.0284751. eCollection 2023. PLoS One. 2023. PMID: 37494413 Free PMC article.
65 results