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A whole genomic CRISPR-Cas9 screen identifies the amino acid transporter SLC43A1 (LAT3) as a major determinant of oxaliplatin sensitivity in colorectal cancer cells.
Pawar NR, Wade HM, Jackson Z, Poungpeth N, Mitchell AV, Jewell CP, Chan D, Robey RW, Batista PJ, Jenkins LM, Gottesman MM. Pawar NR, et al. Among authors: mitchell av. bioRxiv [Preprint]. 2025 Apr 24:2025.04.21.649594. doi: 10.1101/2025.04.21.649594. bioRxiv. 2025. PMID: 40568133 Free PMC article. Preprint.
Atrial fibrillation in former world-class rowers: role of environmental and genetic factors.
Flannery MD, Canovas R, Janssens K, Mitchell AM, D'Ambrosio P, Spencer LW, Rowe SJ, Paratz ED, Claessen G, Myrstad M, Ruiz-Carmona S, Young PE, Ohanian M, Soka M, Rath EM, Giannoulatou E, Johnson R, Yu C, Lacaze P, Elliott AD, Sanders P, Willems R, Heidbuchel H, Kalman JM, Fatkin D, La Gerche A. Flannery MD, et al. Among authors: mitchell am. Eur Heart J. 2025 Jun 25:ehaf369. doi: 10.1093/eurheartj/ehaf369. Online ahead of print. Eur Heart J. 2025. PMID: 40561495
A community-led initiative to de-risk and advance Parkinson's disease therapeutic targets.
Vaiana A, Behr J, Birol R, Blauwendraat C, Casey B, Chowdhury K, Citron M, Crapser J, Dardov V, Ducotterd F, Dumanis S, Dunlop J, Durborow M, Fiske B, Golden J, Hannestad J, Hung W, Kemp J, Kleiman R, Knight A, Koemeter-Cox A, Leuchter B, Logsdon BA, Marreiros R, Miller JE, Mitchell A, Mukherjee P, Navarro G, Nelson MR, Nikolich K, Otis T, Polinski N, Rastegar-Pouyani S, Reith AD, Riley E, Rubin L, Ryten M, Sadick J, Schwabe T, Sherer T, Silvergleid S, Singleton A, St Clair L, Stoehr J, Stone DJ, Sullivan J, Tanenbaum N, Tinelli E, Trimble K, Wang Y, Weninger S, Wiggenhauser N, Wood S, Schoepp D, Buggia-Prevot V, Padmanabhan S, Skibinski G. Vaiana A, et al. Among authors: mitchell a. NPJ Parkinsons Dis. 2025 Jun 20;11(1):179. doi: 10.1038/s41531-025-01039-3. NPJ Parkinsons Dis. 2025. PMID: 40541945 Free PMC article. Review.
4,128 results