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Genetic screens in human cells using the CRISPR-Cas9 system.
Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12.
Science. 2014.
PMID: 24336569
Free PMC article.
Identification and characterization of essential genes in the human genome.
Wang T, Birsoy K, Hughes NW, Krupczak KM, Post Y, Wei JJ, Lander ES, Sabatini DM.
Wang T, et al.
Science. 2015 Nov 27;350(6264):1096-101. doi: 10.1126/science.aac7041. Epub 2015 Oct 15.
Science. 2015.
PMID: 26472758
Free PMC article.
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Large-Scale Single Guide RNA Library Construction and Use for CRISPR-Cas9-Based Genetic Screens.
Wang T, Lander ES, Sabatini DM.
Wang T, et al.
Cold Spring Harb Protoc. 2016 Mar 1;2016(3):pdb.top086892. doi: 10.1101/pdb.top086892.
Cold Spring Harb Protoc. 2016.
PMID: 26933254
Free PMC article.
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