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VH replacement in primary immunoglobulin repertoire diversification.
Sun A, Novobrantseva TI, Coffre M, Hewitt SL, Jensen K, Skok JA, Rajewsky K, Koralov SB. Sun A, et al. Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E458-66. doi: 10.1073/pnas.1418001112. Epub 2015 Jan 21. Proc Natl Acad Sci U S A. 2015. PMID: 25609670 Free PMC article.
Specific increase in potency via structure-based design of a TCR.
Malecek K, Grigoryan A, Zhong S, Gu WJ, Johnson LA, Rosenberg SA, Cardozo T, Krogsgaard M. Malecek K, et al. J Immunol. 2014 Sep 1;193(5):2587-99. doi: 10.4049/jimmunol.1302344. Epub 2014 Jul 28. J Immunol. 2014. PMID: 25070852 Free PMC article.