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Page 1
Tumor-Infiltrating Clonal Hematopoiesis.
Pich O, Bernard E, Zagorulya M, Rowan A, Pospori C, Slama R, Huerga Encabo H, O'Sullivan J, Papazoglou D, Anastasiou P, Iliakis CS, Clark SA, Dijkstra KK, Barbè V, Bailey C, Stonestrom AJ, Enfield KSS, Green M, Brierley CK, Magness A, Pearce DR, Hynds RE, Zaidi R, Rane JK, Álvarez-Prado ÁF, Thol K, Scott R, Bola SK, Hoxha E, Harris SK, Peggs KS, Quezada SA, Hackshaw A, Zaccaria S, Joyce JA, Malanchi I, Berger MF, Jamal-Hanjani M, Wack A, Downward J, Grey W, Lo Celso C, Grönroos E, Rudin CM, Mead AJ, Bonnet D, Papaemmanuil E, Swanton C. Pich O, et al. N Engl J Med. 2025 Apr 24;392(16):1594-1608. doi: 10.1056/NEJMoa2413361. N Engl J Med. 2025. PMID: 40267425 Free PMC article.
Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer.
Enfield KSS, Colliver E, Lee C, Magness A, Moore DA, Sivakumar M, Grigoriadis K, Pich O, Karasaki T, Hobson PS, Levi D, Veeriah S, Puttick C, Nye EL, Green M, Dijkstra KK, Shimato M, Akarca AU, Marafioti T, Salgado R, Hackshaw A; TRACERx consortium; Jamal-Hanjani M, van Maldegem F, McGranahan N, Glass B, Pulaski H, Walk E, Reading JL, Quezada SA, Hiley CT, Downward J, Sahai E, Swanton C, Angelova M. Enfield KSS, et al. Cancer Discov. 2024 Jun 3;14(6):1018-1047. doi: 10.1158/2159-8290.CD-23-1380. Cancer Discov. 2024. PMID: 38581685 Free PMC article.
Tracking Cancer Evolution through the Disease Course.
Bailey C, Black JRM, Reading JL, Litchfield K, Turajlic S, McGranahan N, Jamal-Hanjani M, Swanton C. Bailey C, et al. Cancer Discov. 2021 Apr;11(4):916-932. doi: 10.1158/2159-8290.CD-20-1559. Cancer Discov. 2021. PMID: 33811124 Free PMC article. Review.
ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis.
Hennequart M, Pilley SE, Labuschagne CF, Coomes J, Mervant L, Driscoll PC, Legrave NM, Lee Y, Kreuzaler P, Macintyre B, Panina Y, Blagih J, Stevenson D, Strathdee D, Schneider-Luftman D, Grönroos E, Cheung EC, Yuneva M, Swanton C, Vousden KH. Hennequart M, et al. Cell Rep. 2023 Jun 27;42(6):112562. doi: 10.1016/j.celrep.2023.112562. Epub 2023 May 26. Cell Rep. 2023. PMID: 37245210 Free article.
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution.
Venkatesan S, Angelova M, Puttick C, Zhai H, Caswell DR, Lu WT, Dietzen M, Galanos P, Evangelou K, Bellelli R, Lim EL, Watkins TBK, Rowan A, Teixeira VH, Zhao Y, Chen H, Ngo B, Zalmas LP, Al Bakir M, Hobor S, Grönroos E, Pennycuick A, Nigro E, Campbell BB, Brown WL, Akarca AU, Marafioti T, Wu MY, Howell M, Boulton SJ, Bertoli C, Fenton TR, de Bruin RAM, Maya-Mendoza A, Santoni-Rugiu E, Hynds RE, Gorgoulis VG, Jamal-Hanjani M, McGranahan N, Harris RS, Janes SM, Bartkova J, Bakhoum SF, Bartek J, Kanu N, Swanton C; TRACERx Consortium. Venkatesan S, et al. Cancer Discov. 2021 Oct;11(10):2456-2473. doi: 10.1158/2159-8290.CD-20-0725. Epub 2021 May 4. Cancer Discov. 2021. PMID: 33947663 Free PMC article.
Immune Surveillance in Clinical Regression of Preinvasive Squamous Cell Lung Cancer.
Pennycuick A, Teixeira VH, AbdulJabbar K, Raza SEA, Lund T, Akarca AU, Rosenthal R, Kalinke L, Chandrasekharan DP, Pipinikas CP, Lee-Six H, Hynds RE, Gowers KHC, Henry JY, Millar FR, Hagos YB, Denais C, Falzon M, Moore DA, Antoniou S, Durrenberger PF, Furness AJ, Carroll B, Marceaux C, Asselin-Labat ML, Larson W, Betts C, Coussens LM, Thakrar RM, George J, Swanton C, Thirlwell C, Campbell PJ, Marafioti T, Yuan Y, Quezada SA, McGranahan N, Janes SM. Pennycuick A, et al. Cancer Discov. 2020 Oct;10(10):1489-1499. doi: 10.1158/2159-8290.CD-19-1366. Epub 2020 Jul 20. Cancer Discov. 2020. PMID: 32690541 Free PMC article.