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mTORC1 directly inhibits AMPK to promote cell proliferation under nutrient stress.
Ling NXY, Kaczmarek A, Hoque A, Davie E, Ngoei KRW, Morrison KR, Smiles WJ, Forte GM, Wang T, Lie S, Dite TA, Langendorf CG, Scott JW, Oakhill JS, Petersen J. Ling NXY, et al. Nat Metab. 2020 Jan;2(1):41-49. doi: 10.1038/s42255-019-0157-1. Epub 2020 Jan 20. Nat Metab. 2020. PMID: 31993556 Free PMC article.
Nitrogen regulates AMPK to control TORC1 signaling.
Davie E, Forte GM, Petersen J. Davie E, et al. Curr Biol. 2015 Feb 16;25(4):445-54. doi: 10.1016/j.cub.2014.12.034. Epub 2015 Jan 29. Curr Biol. 2015. PMID: 25639242 Free PMC article.