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Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis.
Bermejo-Rodriguez C, Araos Henríquez J, Caligiuri G, Pinto Teles S, Park Y, Evans A, Barrera LN, Neesse A, Grützmann R, Aust D, Rümmele P, Knösel T, Narita M, Narita M, Campbell F, Öhlund D, Pilarsky C, Dow LE, Humbert PO, Biffi G, Tuveson DA, Perez-Mancera PA. Bermejo-Rodriguez C, et al. Cancer Res. 2024 Sep 16;84(18):2968-2984. doi: 10.1158/0008-5472.CAN-23-3419. Cancer Res. 2024. PMID: 39037766
A large-scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression-free survival.
Beddowes EJ, Ortega Duran M, Karapanagiotis S, Martin A, Gao M, Masina R, Woitek R, Tanner J, Tippin F, Kane J, Lay J, Brouwer A, Sammut SJ, Chin SF, Gale D, Tsui DWY, Dawson SJ, Rosenfeld N, Callari M, Rueda OM, Caldas C. Beddowes EJ, et al. Mol Oncol. 2025 Apr 15. doi: 10.1002/1878-0261.70015. Online ahead of print. Mol Oncol. 2025. PMID: 40231728 Free article.
Modeling Drug Responses and Evolutionary Dynamics Using Patient-Derived Xenografts Reveals Precision Medicine Strategies for Triple-Negative Breast Cancer.
Shea A, Eyal-Lubling Y, Guerrero-Romero D, Manzano Garcia R, Greenwood W, O'Reilly M, Georgopoulou D, Callari M, Lerda G, Wix S, Giovannetti A, Masina R, Esmaeilishirazifard E, Cope W, Martin AG, Nagano A, Young L, Kupczak S, Cheng Y, Bardwell H, Provenzano E, Kane J, Lay J, Grybowicz L, McAdam K, Caldas C, Abraham J, Rueda OM, Bruna A. Shea A, et al. Cancer Res. 2025 Feb 1;85(3):567-584. doi: 10.1158/0008-5472.CAN-24-1703. Cancer Res. 2025. PMID: 39514406 Free PMC article.