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Peptides derived from the CDR3-homologous domain of the CD4 molecule are specific inhibitors of HIV-1 and SIV infection, virus-induced cell fusion, and postinfection viral transmission in vitro. Implications for the design of small peptide anti-HIV therapeutic agents.
Rausch DM, Hwang KM, Padgett M, Voltz AH, Rivas A, Engleman E, Gaston I, McGrath M, Fraser B, Kalyanaraman VS, et al. Rausch DM, et al. Ann N Y Acad Sci. 1990;616:125-48. doi: 10.1111/j.1749-6632.1990.tb17834.x. Ann N Y Acad Sci. 1990. PMID: 2078014 Review.