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2016 1
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67 results

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Page 1
TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction.
Griffin PT, Kane AE, Trapp A, Li J, Arnold M, Poganik JR, Conway RJ, McNamara MS, Meer MV, Hoffman N, Amorim JA, Tian X, MacArthur MR, Mitchell SJ, Mueller AL, Carmody C, Vera DL, Kerepesi C, Ying K, Noren Hooten N, Mitchell JR, Evans MK, Gladyshev VN, Sinclair DA. Griffin PT, et al. Nat Aging. 2024 Feb;4(2):261-274. doi: 10.1038/s43587-023-00555-2. Epub 2024 Jan 10. Nat Aging. 2024. PMID: 38200273 Free PMC article.
p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells.
Miller KN, Li B, Pierce-Hoffman HR, Patel S, Lei X, Rajesh A, Teneche MG, Havas AP, Gandhi A, Macip CC, Lyu J, Victorelli SG, Woo SH, Lagnado AB, LaPorta MA, Liu T, Dasgupta N, Li S, Davis A, Korotkov A, Hultenius E, Gao Z, Altman Y, Porritt RA, Garcia G, Mogler C, Seluanov A, Gorbunova V, Kaech SM, Tian X, Dou Z, Chen C, Passos JF, Adams PD. Miller KN, et al. Nat Commun. 2025 Mar 5;16(1):2229. doi: 10.1038/s41467-025-57229-3. Nat Commun. 2025. PMID: 40044657 Free PMC article.
Linking Aging to Cancer: The Role of Chromatin Biology.
Corveleyn L, Sen P, Adams P, Sidoli S. Corveleyn L, et al. J Gerontol A Biol Sci Med Sci. 2024 Jul 1;79(7):glae133. doi: 10.1093/gerona/glae133. J Gerontol A Biol Sci Med Sci. 2024. PMID: 38761362 Free PMC article. Review.
SIRT2 transgenic over-expression does not impact lifespan in mice.
Wu LE, Fiveash CE, Bentley NL, Kang MJ, Govindaraju H, Barbour JA, Wilkins BP, Hancock SE, Madawala R, Das A, Massudi H, Li C, Kim LJ, Wong ASA, Marinova MB, Sultani G, Das A, Youngson NA, Le Couteur DG, Sinclair DA, Turner N. Wu LE, et al. Aging Cell. 2023 Dec;22(12):e14027. doi: 10.1111/acel.14027. Epub 2023 Nov 27. Aging Cell. 2023. PMID: 38009412 Free PMC article.
Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome.
Ho WJ, Marinova MB, Listijono DR, Bertoldo MJ, Richani D, Kim LJ, Brown A, Riepsamen AH, Cabot S, Frost ER, Bustamante S, Zhong L, Selesniemi K, Wong D, Madawala R, Marchante M, Goss DM, Li C, Araki T, Livingston DJ, Turner N, Sinclair DA, Walters KA, Homer HA, Gilchrist RB, Wu LE. Ho WJ, et al. EMBO Mol Med. 2024 Oct;16(10):2583-2618. doi: 10.1038/s44321-024-00119-w. Epub 2024 Aug 21. EMBO Mol Med. 2024. PMID: 39169162 Free PMC article.
At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle.
Chambers TL, Wells J, Koopmans PJ, Morena F, Malik ZB, Greene NP, Filareto A, Franti M, Sini P, Weinstabl H, Brooke RT, Milčiūtė M, Gordevičius J, Horvath S, Wen Y, Dungan CM, Murach KA. Chambers TL, et al. Aging Cell. 2025 Apr 21:e70068. doi: 10.1111/acel.70068. Online ahead of print. Aging Cell. 2025. PMID: 40259517 Free article.
67 results