C6563/A10192/CRUK_/Cancer Research UK/United Kingdom[Grants and Funding] - Search Results

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2009	2
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A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage.

Cortes Ledesma F, El Khamisy SF, Zuma MC, Osborn K, Caldecott KW. Cortes Ledesma F, et al. Nature. 2009 Oct 1;461(7264):674-8. doi: 10.1038/nature08444. Nature. 2009. PMID: 19794497

Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair.

Reynolds JJ, Walker AK, Gilmore EC, Walsh CA, Caldecott KW. Reynolds JJ, et al. Nucleic Acids Res. 2012 Aug;40(14):6608-19. doi: 10.1093/nar/gks318. Epub 2012 Apr 15. Nucleic Acids Res. 2012. PMID: 22508754 Free PMC article.

Enhanced radiosensitization of human glioma cells by combining inhibition of poly(ADP-ribose) polymerase with inhibition of heat shock protein 90.

Dungey FA, Caldecott KW, Chalmers AJ. Dungey FA, et al. Mol Cancer Ther. 2009 Aug;8(8):2243-54. doi: 10.1158/1535-7163.MCT-09-0201. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671736 Free PMC article.

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