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Genetic crosses within and between species of Cryptosporidium.
Shaw S, Cohn IS, Baptista RP, Xia G, Melillo B, Agyabeng-Dadzie F, Kissinger JC, Striepen B. Shaw S, et al. Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2313210120. doi: 10.1073/pnas.2313210120. Epub 2023 Dec 26. Proc Natl Acad Sci U S A. 2024. PMID: 38147547 Free PMC article.
Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses.
Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, Christian DA, Striepen B, Hunter CA. Haskins BE, et al. Mucosal Immunol. 2024 Jun;17(3):387-401. doi: 10.1016/j.mucimm.2024.03.003. Epub 2024 Mar 18. Mucosal Immunol. 2024. PMID: 38508522 Free PMC article.
Intestinal cDC1s provide IL-12 dependent and independent functions required for CD4+ T cell-mediated resistance to Cryptosporidium.
Cohn IS, Wallbank BA, Haskins BE, O'Dea KM, Pardy RD, Shaw S, Merolle MI, Gullicksrud JA, Christian DA, Striepen B, Hunter CA. Cohn IS, et al. bioRxiv [Preprint]. 2023 Nov 13:2023.11.11.566669. doi: 10.1101/2023.11.11.566669. bioRxiv. 2023. Update in: J Exp Med. 2024 Jul 1;221(7):e20232067. doi: 10.1084/jem.20232067. PMID: 38014026 Free PMC article. Updated. Preprint.
Analysis of intestinal epithelial cell responses to Cryptosporidium highlights the temporal effects of IFN-γ on parasite restriction.
Pardy RD, Walzer KA, Wallbank BA, Byerly JH, O'Dea KM, Cohn IS, Haskins BE, Roncaioli JL, Smith EJ, Buenconsejo GY, Striepen B, Hunter CA. Pardy RD, et al. bioRxiv [Preprint]. 2023 Nov 16:2023.11.14.567008. doi: 10.1101/2023.11.14.567008. bioRxiv. 2023. Update in: PLoS Pathog. 2024 May 8;20(5):e1011820. doi: 10.1371/journal.ppat.1011820. PMID: 38014210 Free PMC article. Updated. Preprint.