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Page 1
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Travers JG, Wennersten SA, Peña B, Bagchi RA, Smith HE, Hirsch RA, Vanderlinden LA, Lin YH, Dobrinskikh E, Demos-Davies KM, Cavasin MA, Mestroni L, Steinkühler C, Lin CY, Houser SR, Woulfe KC, Lam MPY, McKinsey TA. Travers JG, et al. Circulation. 2021 May 11;143(19):1874-1890. doi: 10.1161/CIRCULATIONAHA.120.046462. Epub 2021 Mar 8. Circulation. 2021. PMID: 33682427 Free PMC article.
A Phosphatase Anchor Weighs on the Heart.
Woulfe KC, Travers JG, McKinsey TA. Woulfe KC, et al. Circulation. 2020 Sep 8;142(10):963-966. doi: 10.1161/CIRCULATIONAHA.120.049268. Epub 2020 Sep 8. Circulation. 2020. PMID: 32897751 Free PMC article. No abstract available.
Sex-specific responses to slow progressive pressure overload in a large animal model of HFpEF.
Eaton DM, Berretta RM, Lynch JE, Travers JG, Pfeiffer RD, Hulke ML, Zhao H, Hobby ARH, Schena G, Johnson JP, Wallner M, Lau E, Lam MPY, Woulfe KC, Tucker NR, McKinsey TA, Wolfson MR, Houser SR. Eaton DM, et al. Am J Physiol Heart Circ Physiol. 2022 Oct 1;323(4):H797-H817. doi: 10.1152/ajpheart.00374.2022. Epub 2022 Sep 2. Am J Physiol Heart Circ Physiol. 2022. PMID: 36053749 Free PMC article.
ABHD5 cleaves HDAC4 to benefit the heart.
Travers JG, McKinsey TA. Travers JG, et al. Nat Metab. 2019 Nov;1(11):1034-1035. doi: 10.1038/s42255-019-0141-9. Nat Metab. 2019. PMID: 32694866 No abstract available.