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PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damage.
Oncogene. 2010 Jul 8;29(27):3881-95. doi: 10.1038/onc.2010.153. Epub 2010 May 10.
Oncogene. 2010.
PMID: 20453876
Free PMC article.
PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation.
Bobrovnikova-Marjon E, Pytel D, Riese MJ, Vaites LP, Singh N, Koretzky GA, Witze ES, Diehl JA.
Bobrovnikova-Marjon E, et al.
Mol Cell Biol. 2012 Jun;32(12):2268-78. doi: 10.1128/MCB.00063-12. Epub 2012 Apr 9.
Mol Cell Biol. 2012.
PMID: 22493067
Free PMC article.
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PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation.
Bobrovnikova-Marjon E, Hatzivassiliou G, Grigoriadou C, Romero M, Cavener DR, Thompson CB, Diehl JA.
Bobrovnikova-Marjon E, et al.
Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16314-9. doi: 10.1073/pnas.0808517105. Epub 2008 Oct 13.
Proc Natl Acad Sci U S A. 2008.
PMID: 18852460
Free PMC article.
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