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Formyl-peptide receptor type 2 activation mitigates heart and lung damage in inflammatory arthritis.
Margraf A, Chen J, Christoforou M, Claria-Ribas P, Henriques Schneider A, Cecconello C, Bu W, Imbert PRC, Wright TD, Russo S, Blacksell IA, Koenis DS, Dalli J, Lupisella JA, Wurtz NR, Garcia RA, Cooper D, Norling LV, Perretti M. Margraf A, et al. EMBO Mol Med. 2025 May;17(5):1153-1183. doi: 10.1038/s44321-025-00227-1. Epub 2025 Apr 3. EMBO Mol Med. 2025. PMID: 40181186 Free PMC article.
Senescent endothelial cells promote pathogenic neutrophil trafficking in inflamed tissues.
Rolas L, Stein M, Barkaway A, Reglero-Real N, Sciacca E, Yaseen M, Wang H, Vazquez-Martinez L, Golding M, Blacksell IA, Giblin MJ, Jaworska E, Bishop CL, Voisin MB, Gaston-Massuet C, Fossati-Jimack L, Pitzalis C, Cooper D, Nightingale TD, Lopez-Otin C, Lewis MJ, Nourshargh S. Rolas L, et al. EMBO Rep. 2024 Sep;25(9):3842-3869. doi: 10.1038/s44319-024-00182-x. Epub 2024 Jun 25. EMBO Rep. 2024. PMID: 38918502 Free PMC article.