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Orally Inhaled Flecainide for Conversion of Atrial Fibrillation to Sinus Rhythm: INSTANT Phase 2 Trial.
Ruskin JN, Camm AJ, Dufton C, Woite-Silva AC, Tuininga Y, Badings E, De Jong JSSG, Oosterhof T, Aksoy I, Kuijper AFM, Van Gelder IC, van Dijk V, Nuyens D, Schellings D, Lee MY, Kowey PR, Crijns HJGM, Maupas J, Belardinelli L; INSTANT Investigators. Ruskin JN, et al. JACC Clin Electrophysiol. 2024 Jun;10(6):1021-1033. doi: 10.1016/j.jacep.2024.02.021. Epub 2024 Apr 10. JACC Clin Electrophysiol. 2024. PMID: 38613545 Free article. Clinical Trial.
Open-Label, Multicenter Study of Flecainide Acetate Oral Inhalation Solution for Acute Conversion of Recent-Onset, Symptomatic Atrial Fibrillation to Sinus Rhythm.
Crijns HJGM, Elvan A, Al-Windy N, Tuininga YS, Badings E, Aksoy I, Van Gelder IC, Madhavapeddi P, Camm AJ, Kowey PR, Ruskin JN, Belardinelli L; INSTANT Investigators*. Crijns HJGM, et al. Circ Arrhythm Electrophysiol. 2022 Mar;15(3):e010204. doi: 10.1161/CIRCEP.121.010204. Epub 2022 Feb 24. Circ Arrhythm Electrophysiol. 2022. PMID: 35196871 Free article.
Effect of Intravenous Tirofiban Versus Placebo on Excellent Outcome in Patients With Acute Ischemic Stroke: The Multicenter, Randomized INSTANT Trial Protocol.
Zhang F, Xiao M, Zhang C, Yuan G, Xie Z, Yin Y, Zhou R, Yuan S, Xiao G, Mei D, Zeng X, Liu H, Li H, Liu H, Tan J, Chen B, Fu Q, Li B, Lai J, Sun W, Xie S, Lai Z, Qiu Z, Jiang Z, Liu X, Zeng G; INSTANT investigators. Zhang F, et al. J Am Heart Assoc. 2025 Jun 27:e038536. doi: 10.1161/JAHA.124.038536. Online ahead of print. J Am Heart Assoc. 2025. PMID: 40576038 Free article.